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Leukocyte adhesion deficiency 1

MONDO:0007293

Leukocyte adhesion deficiency type I (LAD-I) is a form of LAD characterized by life-threatening, recurrent bacterial infections.

Also known as: leukocyte adhesion deficiency, ITGB2 leukocyte adhesion deficiency, LAD-I, LAD1, LFA-I deficiency, LFA1 immunodeficiency, lad-I, lad-type I

7 clinical trials for this condition and its sub-types, 7 tagged with Leukocyte adhesion deficiency 1 itself.

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↑ Leukocyte adhesion deficiency (7)

Including sub-types (7) Tagged with Leukocyte adhesion deficiency 1 (7)

Trials to join now! 6 Not yet finished but already full! 1

Gene therapy for rare immune disease shows promise in Long-Term study

Disease control Ongoing

This study follows 9 people with a rare immune disorder called LAD-I who received a one-time gene therapy that adds a working copy of the ITGB2 gene to their own blood stem cells. Researchers want to see if the treatment safely controls the disease over many years and helps patie…

Sponsor: Rocket Pharmaceuticals Inc. • Aim: Disease control

Last updated Jun 27, 2026 08:05 UTC

Leukocyte adhesion deficiency 1

Where it sits in the disease tree

Gene therapy for rare immune disease shows promise in Long-Term study