Please sign in to follow a disease.
Leukemia, myeloid, accelerated-phase
MONDO:0021367The phase of chronic myeloid leukemia following the chronic phase (leukemia, myeloid, chronic-phase), where there are increased systemic symptoms, worsening cytopenias, and refractory leukocytosis.
Also known as: Accelerated Phase CML, Accelerated Phase Chronic Granulocytic Leukaemia, Accelerated Phase Chronic Granulocytic Leukemia, Accelerated Phase Chronic Myelocytic Leukaemia, Accelerated Phase Chronic Myelocytic Leukemia, Accelerated Phase Chronic Myelogenous Leukaemia, Accelerated Phase Chronic Myelogenous Leukemia, Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive
3093 clinical trials for this condition and its sub-types, 30 tagged with Leukemia, myeloid, accelerated-phase itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →-
Drug cocktail aims to tame advanced leukemia
Disease control CompletedThis phase 2 trial is testing whether combining two drugs, ponatinib and 5-azacitidine, can improve survival in people with advanced chronic myeloid leukemia (CML). The study includes adults whose CML has progressed to an accelerated phase or a more aggressive blast crisis. Parti…
Phase 2 • Sponsor: Versailles Hospital • Aim: Disease control
Last updated Jul 08, 2026 00:00 UTC
-
New drug cocktail shows promise against tough leukemia
Disease control CompletedThis study tested a combination of three drugs (decitabine, venetoclax, and ponatinib) in 20 adults with a rare, aggressive leukemia called Philadelphia chromosome-positive acute myeloid leukemia or chronic myelogenous leukemia in blast phase. The goal was to see if the drugs cou…
Phase 2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 13:02 UTC
-
Selective immune cell removal may tame transplant complications
Disease control CompletedThis study tested whether removing a specific type of immune cell (naïve T cells) from donor stem cell grafts could prevent graft-versus-host disease (GVHD) after a stem cell transplant for blood cancers. The trial enrolled 84 patients who received high- or medium-intensity chemo…
Phase 2 • Sponsor: Fred Hutchinson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC