Leishmaniasis
MONDO:0011989Infectious disease that is transmitted through the bite of hematophagous female phlebotomine sand flies. The clinical spectrum ranges from asymptomatic to clinically overt disease which can remain localized to the skin or disseminate to the upper oral and respiratory mucous membranes or throughout the reticulo-endothelial system. Three main clinical syndromes have been described: visceral (or Kala-Azar; with fever, weight loss, hepatosplenomegaly), cutaneous, and mucocutaneous leishmaniasis (cutaneous or mucocutaneous ulceration).
Also known as: cutaneous leishmaniasis (subtype), visceral leishmaniasis (subtype)
28 clinical trials for this condition and its sub-types, 8 tagged with Leishmaniasis itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Leishmaniasis
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Cutaneous leishmaniasis 14 trials
1 sub-type
- Leishmaniasis, diffuse cutaneous 0 trials
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Visceral leishmaniasis 14 trials
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Mucocutaneous leishmaniasis 3 trials
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Could a flower extract heal parasitic skin ulcers? new trial seeks answers
Disease control Recruiting nowThis phase 3 trial tests whether a plant-based tincture made from arnica flowers can safely and effectively heal skin ulcers caused by cutaneous leishmaniasis, a parasitic disease spread by sandflies. About 96 people aged 12 and older with confirmed infection will receive either …
Phase 3 • Sponsor: Universidad de Antioquia • Aim: Disease control
Last updated Jun 27, 2026 12:04 UTC
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New DNA test could speed up diagnosis of three major parasitic infections
Diagnosis Recruiting nowThis study aims to see if a new PCR-based test can diagnose malaria, leishmania, and pneumocystis infections faster and more accurately than current methods. Researchers will analyze about 200 stored samples from patients. The goal is to improve diagnosis and species identificati…
Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia • Aim: Diagnosis
Last updated Jun 27, 2026 08:02 UTC
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Scientists study leishmania infections to improve diagnosis and care
Knowledge-focused Recruiting nowThis study looks at how leishmaniasis infections progress and respond to treatment. It involves up to 289 people aged 3 to 100 with known or suspected leishmaniasis. Researchers will collect blood and tissue samples to learn more about the disease and test different treatments. T…
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Knowledge-focused
Last updated Sep 02, 2026 00:00 UTC
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Can leishmania antigens trigger a protective immune response?
Knowledge-focused Recruiting nowThis study investigates whether six specific Leishmania antigens can activate T-cells in blood and tissue samples from patients with visceral and cutaneous leishmaniasis. Researchers will compare responses before and after treatment, and against healthy volunteers, to see if thes…
Sponsor: Institute of Tropical Medicine, Belgium • Aim: Knowledge-focused
Last updated Aug 26, 2026 00:00 UTC
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10,000 people tested: Cambodia's massive disease hunt begins
Knowledge-focused Recruiting nowThis study will test 10,000 people in Cambodia for 57 different infectious diseases, including dengue, flu, and malaria. Researchers want to understand how these diseases spread and who is at risk. The goal is to give local health authorities the information they need to create b…
Sponsor: Institut Pasteur du Cambodge • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC