Leiomyosarcoma of the corpus uteri
MONDO:0016262An aggressive malignant smooth muscle neoplasm, arising from the uterine corpus. It is characterized by a proliferation of neoplastic spindle cells.
Also known as: Uterine Leiomyosarcoma, body of uterus leiomyosarcoma, corpus uteri leiomyosarcoma, leiomyosarcoma - uterus, leiomyosarcoma of body of uterus, leiomyosarcoma of corpus uteri, leiomyosarcoma of the body of uterus, leiomyosarcoma of the corpus uteri
2930 clinical trials for this condition and its sub-types, 9 tagged with Leiomyosarcoma of the corpus uteri itself.
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Sub-types of Leiomyosarcoma of the corpus uteri
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Uterine corpus myxoid leiomyosarcoma 0 trials
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Could chemo keep uterine sarcoma at bay? new trial seeks answers
Disease control Recruiting nowThis Phase II trial is testing whether a combination of two chemotherapy drugs, doxorubicin and trabectedin, can help prevent uterine leiomyosarcoma from coming back after surgery. The study enrolls 48 patients with high-risk, early-stage disease who have had their tumor fully re…
Phase 2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Aug 22, 2026 00:00 UTC
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Can a common breast cancer drug slow uterine sarcoma?
Disease control Recruiting nowThis phase 2 trial tests whether the drug letrozole can extend the time before uterine leiomyosarcoma returns after initial treatment. About 40 women with early-stage disease will be randomly assigned to take letrozole daily or to be observed without treatment. The main goal is t…
Phase 2 • Sponsor: GOG Foundation • Aim: Disease control
Last updated Aug 01, 2026 00:00 UTC
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Could a pill that blocks estrogen help fight rare uterine cancers?
Disease control Recruiting nowThis phase 2 trial is testing elacestrant, a pill that breaks down estrogen receptors, in 30 people with advanced uterine sarcomas that are fueled by estrogen. The goal is to see if the drug can shrink tumors or slow their growth. Participants must have tumors that strongly expre…
Phase 2 • Sponsor: Dana-Farber Cancer Institute • Aim: Disease control
Last updated Jun 27, 2026 12:37 UTC
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AI takes on mysterious uterine tumors: a new hope for accurate diagnosis
Knowledge-focused Recruiting nowThis study is testing whether artificial intelligence can help doctors better classify and predict the behavior of rare smooth muscle tumors of the uterus, including those that are hard to diagnose (called STUMP). Researchers will train AI models on digital images of tumor tissue…
Sponsor: Institut Bergonié • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC