Leiomyosarcoma of the corpus uteri
MONDO:0016262An aggressive malignant smooth muscle neoplasm, arising from the uterine corpus. It is characterized by a proliferation of neoplastic spindle cells.
Also known as: Uterine Leiomyosarcoma, body of uterus leiomyosarcoma, corpus uteri leiomyosarcoma, leiomyosarcoma - uterus, leiomyosarcoma of body of uterus, leiomyosarcoma of corpus uteri, leiomyosarcoma of the body of uterus, leiomyosarcoma of the corpus uteri
2939 clinical trials for this condition and its sub-types, 9 tagged with Leiomyosarcoma of the corpus uteri itself.
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Sub-types of Leiomyosarcoma of the corpus uteri
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Uterine corpus myxoid leiomyosarcoma 0 trials
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New drug cocktail aims to fight rare uterine cancer after chemo fails
Disease control OngoingThis study tests whether combining olaparib and temozolomide works better than standard drugs (trabectedin or pazopanib) for people with advanced uterine leiomyosarcoma that has spread or cannot be removed by surgery and has stopped responding to initial chemotherapy. About 74 pa…
Phase 2/3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Aug 05, 2026 00:00 UTC
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New drug combo shows promise for rare uterine cancer
Disease control OngoingThis study tests two drugs—olaparib and temozolomide—together in 23 people with advanced uterine leiomyosarcoma that has spread or cannot be removed by surgery. Olaparib blocks a protein that helps cancer cells repair themselves, while temozolomide damages cancer cell DNA. The go…
Phase 2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Aug 02, 2026 00:00 UTC
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New drug cocktail shows promise for rare sarcomas
Disease control OngoingThis phase II trial tests whether combining cabozantinib (a targeted therapy) with temozolomide (a chemotherapy drug) can slow tumor growth in people with advanced leiomyosarcoma or other soft tissue sarcomas that cannot be surgically removed or have spread. About 96 participants…
Phase 2 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Jun 27, 2026 12:28 UTC