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Laryngeal disorder
MONDO:0004382A non-neoplastic or neoplastic disorder that affects the larynx. Representative examples include laryngitis, vocal cord polyp, squamous papilloma, and carcinoma.
Also known as: disease of larynx, disease or disorder of larynx, disorder of larynx, disorder of the larynx, laryngeal disease, laryngeal disorder, larynx disease, larynx disease or disorder
259 clinical trials for this condition and its sub-types, 44 tagged with Laryngeal disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Laryngeal disorder
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Laryngeal neoplasm 72 trials · 138 incl. sub-types
6 sub-types
- Larynx cancer 41 trials · 125 incl. sub-types Sub-types →
- Glottis neoplasm 3 trials · 12 incl. sub-types Sub-types →
- Supraglottis neoplasm 0 trials · 3 incl. sub-types Sub-types →
- Benign laryngeal neoplasm 1 trial · 2 incl. sub-types Sub-types →
- Subglottis neoplasm 0 trials · 1 incl. sub-types Sub-types →
- Laryngeal neuroendocrine neoplasm 0 trials Sub-types →
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Spasmodic dystonia 39 trials
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Voice disorders 18 trials
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Laryngeal abductor paralysis 10 trials
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Congenital laryngeal palsy 9 trials
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Laryngitis 2 trials · 8 incl. sub-types
4 sub-types
- Acute laryngitis 1 trial · 6 incl. sub-types Sub-types →
- Laryngotracheitis 1 trial · 5 incl. sub-types Sub-types →
- Chronic laryngitis 0 trials
- Laryngeal tuberculosis 0 trials
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Congenital subglottic stenosis 7 trials
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Idiopathic subglottic stenosis 7 trials
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Polyp of vocal cord 7 trials
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Laryngostenosis 3 trials
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Congenital laryngomalacia 1 trial
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H syndrome 0 trials
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Acquired laryngomalacia 0 trials
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Congenital laryngeal cyst 0 trials
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Congenital laryngeal web 0 trials
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Laryngeal diphtheria 0 trials
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Laryngeal granuloma 0 trials
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Laryngocele 0 trials
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Larynx atresia 0 trials
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Primary laryngeal lymphangioma 0 trials
Most studied deeper sub-types
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New hope for head and neck cancer: drug combo trial underway
Disease control OngoingThis phase 3 trial tests whether adding monalizumab to the standard drug cetuximab helps people with recurrent or metastatic head and neck cancer live longer. The study includes 370 adults who have already tried an immune checkpoint inhibitor and platinum-based chemotherapy. Part…
Phase 3 • Sponsor: AstraZeneca • Aim: Disease control
Last updated Sep 11, 2026 00:00 UTC
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Voice box transplant trial hopes to give speech back to patients
Disease control PausedThis study tests whether transplanting a donor voice box (larynx) can safely restore voice, swallowing, and breathing in people with severe larynx damage or who have had their larynx removed. Ten adults will receive the transplant and be followed for five years. The trial is curr…
Sponsor: Mayo Clinic • Aim: Disease control
Last updated Jul 24, 2026 00:00 UTC
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Could an immunotherapy combo replace harsh chemo for head and neck cancer?
Disease control OngoingThis phase II trial tests whether combining the immunotherapy drug durvalumab (Imfinzi) with radiation therapy can effectively treat intermediate-risk head and neck cancer after surgery, while causing fewer serious side effects than the standard cisplatin-based chemo-radiation. T…
Phase 2 • Sponsor: UNC Lineberger Comprehensive Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 14:03 UTC
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New drug cocktail shows promise in battling advanced head and neck cancer
Disease control OngoingThis study tests whether adding two drugs, niraparib and dostarlimab, to standard radiation therapy can better control advanced head and neck cancer. About 34 adults with stage III or IV cancer will receive the drugs before, during, and after radiation. The goal is to see if this…
Phase 1/2 • Sponsor: Grupo Español de Tratamiento de Tumores de Cabeza y Cuello • Aim: Disease control
Last updated Jun 27, 2026 13:03 UTC
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New chemo combo aims to help laryngeal cancer patients keep their voice
Disease control OngoingThis Phase 3 trial tests whether giving a three-drug chemotherapy regimen (docetaxel, cisplatin, and fluorouracil) before radiotherapy helps people with advanced laryngeal or hypopharyngeal cancer avoid losing their voice box. The standard approach is to give cisplatin during rad…
Phase 3 • Sponsor: Groupe Oncologie Radiotherapie Tete et Cou • Aim: Disease control
Last updated Jun 26, 2026 12:59 UTC
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New CT scanner could sharpen view of throat cancer
Diagnosis By invitation onlyThis study tests a new type of CT scan, called Photon-Counting CT, to see if it can more accurately show how far laryngeal cancer has spread. Sixty adults with laryngeal cancer will get this scan while making a sound, which may help separate normal tissues from tumor. The goal is…
Sponsor: Humanitas University • Aim: Diagnosis
Last updated Jun 27, 2026 12:36 UTC
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Can a surgical flap prevent a common complication after throat cancer surgery?
Knowledge-focused OngoingThis study looks at 400 people who had surgery to remove throat cancer (laryngectomy or pharyngolaryngectomy). The goal is to find out which factors, like using a surgical flap or muscle loss (sarcopenia), increase the risk of a fistula—a leak that can cause infection. Researcher…
Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC