Lambert-Eaton myasthenic syndrome
MONDO:0018556Lambert-Eaton myasthenic syndrome (LEMS) is an autoimmune, presynaptic disorder of neuromuscular transmission characterized by fluctuating muscle weakness and autonomic dysfunction frequently associated with small-cell lung cancer (SCLC).
Also known as: Eaton Lambert syndrome, Eaton-Lambert syndrome, Lambert Eaton myasthenic syndrome, Lambert Eaton syndrome, Lambert-Eaton syndrome, myasthenic syndrome of Lambert-Eaton, myasthenic-myopathic syndrome of Lambert-Eaton
4 clinical trials for this condition and its sub-types, 4 tagged with Lambert-Eaton myasthenic syndrome itself.
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Could a stem cell transplant stop the immune system from attacking the brain?
Disease control OngoingThis phase 2 trial tests whether high-dose chemotherapy followed by a stem cell transplant can stop the immune system from attacking the nervous system in people with autoimmune neurologic diseases like multiple sclerosis and stiff person syndrome. The treatment aims to weaken th…
Phase 2 • Sponsor: Fred Hutchinson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 09:08 UTC
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New test could predict falls in muscle disease patients
Diagnosis By invitation onlyThis study aims to create a simple test battery to determine fall risk in people with neuromuscular disorders, such as muscular dystrophy or ALS. Researchers will assess 108 participants using several physical tests like walking, standing, and rising from a chair. The goal is to …
Sponsor: LMU Klinikum • Aim: Diagnosis
Last updated Jun 26, 2026 16:30 UTC
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Could a hidden nerve condition be more common in lung cancer than we think?
Knowledge-focused CancelledThis study is looking at how often people with small cell lung cancer also have symptoms of Lambert-Eaton myasthenic syndrome (LEMS), a condition that affects the nerves and can cause muscle weakness. Researchers will review medical records and check for LEMS symptoms in adults d…
Sponsor: Addario Lung Cancer Medical Institute • Aim: Knowledge-focused
Last updated Aug 06, 2026 00:00 UTC