Lactic acidosis
MONDO:0006040Metabolic acidosis characterized by the accumulation of lactate in the body. It is caused by tissue hypoxia.
8 clinical trials for this condition and its sub-types, 8 tagged with Lactic acidosis itself.
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Sub-types of Lactic acidosis
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Acquired lactic acidosis 0 trials
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New pill aims to ease fatigue and brain fog in rare mitochondrial disease
Disease control CompletedThis Phase 2b trial tests an oral drug called zagociguat in 43 adults with MELAS syndrome, a rare genetic disorder that causes fatigue, muscle weakness, and stroke-like episodes. Participants take either 15 mg, 30 mg, or a placebo daily for 12 weeks. The study measures changes in…
Phase 2 • Sponsor: Tisento Therapeutics • Aim: Disease control
Last updated Jul 09, 2026 00:00 UTC
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New drug shows promise for rare energy disorder
Disease control CompletedThis study tested a new drug called OMT-28 in 28 people with primary mitochondrial disease, a condition that affects how cells produce energy. Participants took the drug once daily for 6 months, and researchers measured safety, blood markers of inflammation, and symptoms like fat…
Phase 2 • Sponsor: Omeicos Therapeutics GmbH • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC
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Fingertip test may rival blood test in sepsis care
Knowledge-focused CompletedThis study looked at 192 adults with septic shock to see if a simple finger-pressure test (capillary refill time) could predict outcomes as well as a standard blood test (lactate level). Researchers measured both at the same time and tracked which patients got worse or died withi…
Sponsor: Gulhane Training and Research Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC