Lactation disease

This phase 2 trial tests whether a single dose of cabergoline can prevent breast engorgement, milk leakage, and tenderness after abortion or pregnancy loss at 12-18 weeks. About 348 participants will receive either cabergoline or a placebo right after the procedure and report sym…

This study tests whether teaching new mothers how to do acupressure on themselves can help them breastfeed exclusively for longer. 360 mothers will either get standard care or also learn acupressure within 48 hours after giving birth. Researchers will track breastfeeding rates at…

This study tests whether a special back massage, called oxytocin massage, can help new mothers who feel they aren't making enough milk. The massage aims to trigger the body's natural release of oxytocin, a hormone that helps milk flow. Researchers will measure mothers' confidence…

This study will measure how much of the drug mirikizumab passes into breast milk in 14 breastfeeding women who take it for inflammatory bowel disease. Participants will provide milk samples over several weeks. The goal is to understand potential exposure to nursing infants, helpi…

This study investigates whether injected GLP-1 receptor agonists, such as semaglutide, affect breastmilk production and its nutritional makeup in breastfeeding mothers. Participants will have their milk production measured before and after starting the medication, and milk sample…

This study explores how severe sleep deprivation in the first 48 hours after childbirth impacts a mother's motivation to breastfeed and her breastfeeding success. Researchers will track 167 new mothers, including those who had C-sections, using surveys and feeding assessments. Th…

This study looks at how exercise and physical activity during and after pregnancy change the makeup of breast milk. Researchers want to see if these changes affect how babies use energy and grow, which could help prevent childhood obesity. The study will follow 200 mothers and th…

This study tests whether teaching mindfulness and meditation to mothers with babies in the neonatal ICU can increase breastmilk volume and reduce stress. Forty mothers will be split into two groups: one gets standard care, the other adds mindfulness training. Researchers will mea…

This study looks at how prescription and over-the-counter medicines taken by breastfeeding mothers get into their breast milk and whether they might affect their babies. Researchers will collect milk and urine samples from 250 women and ask about infant symptoms. The goal is to p…