Keratolytic winter erythema

Keratolytic winter erythema is a rare epidermal disease, characterized by recurrent centrifugal palmoplantar peeling and erythema presenting seasonal variation (cold weather). Skin lesions may spread to the dorsum of hands and feet and to the interdigital spaces. Lower legs, knees and thighs may also be involved. Episodes may be preceded by itch and hyperhidrosis. Skin biopsy reveals an epidermal spongiosis with clefting in the stratum corneum, followed by regrowth. Keratolytic winter erythema follows an autosomal dominant mode of transmission.

Also known as: Erythrokeratolysis hiemalis, Oudtshoorn disease, keratolytic winter erythema, Erythrokeratolysis hiemalis ichthyosis, KWE, Oudtshoorn skin, Oudtshoorn skin disease, keratolytic WINTER erythema

0 clinical trials for this condition and its sub-types, 0 tagged with Keratolytic winter erythema itself.