Junctional epidermolysis bullosa

MONDO:0017612

Junctional epidermolysis bullosa (JEB) is a form of inherited epidermolysis bullosa characterized by involvement of the skin and mucous membranes, and is defined by the formation of blistering lesions between the epidermis and the dermis at the lamina lucida level of the cutaneous basement membrane zone and by healing of lesions with atrophy and/or exuberant granulation tissue formation.

Also known as: EBJ, JEB, epidermolysis bullosa atrophicans, junctional epidermolysis bullosa, epidermolysis bullosa hereditaria letalis, epidermolysis bullosa, junctional

9 clinical trials for this condition and its sub-types, 6 tagged with Junctional epidermolysis bullosa itself.

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Where it sits in the disease tree

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↑ Inherited epidermolysis bullosa (38)

Sub-types of Junctional epidermolysis bullosa

Junctional epidermolysis bullosa, non-Herlitz type 2 trials
2 sub-types
- Generalized junctional epidermolysis bullosa non-Herlitz type 0 trials
- Localized junctional epidermolysis bullosa, non-Herlitz type 0 trials
Epidermolysis bullosa, junctional 2A, intermediate 0 trials
Epidermolysis bullosa, junctional 2B, severe 0 trials
Epidermolysis bullosa, junctional 3A, intermediate 0 trials
Epidermolysis bullosa, junctional 3B, severe 0 trials
Epidermolysis bullosa, junctional 4, intermediate 0 trials
Epidermolysis bullosa, junctional 5A, intermediate 0 trials
Epidermolysis bullosa, junctional 6, with pyloric atresia 0 trials
Epidermolysis bullosa, junctional 7, with interstitial lung disease and nephrotic syndrome 0 trials
Junctional epidermolysis bullosa Herlitz type 0 trials
Junctional epidermolysis bullosa inversa 0 trials
Junctional epidermolysis bullosa with pyloric atresia 0 trials
Laryngo-onycho-cutaneous syndrome 0 trials
Late-onset junctional epidermolysis bullosa 0 trials
Late-onset localized junctional epidermolysis bullosa-intellectual disability syndrome 0 trials

Including sub-types (9) Tagged with Junctional epidermolysis bullosa (6)

Trials to join now! 4 Not yet recruiting 1 Not yet finished but already full! 3 Completed 1

CBD oil may soothe itch in kids with rare skin disease

Symptom relief Completed

This study tested whether cannabidiol (CBD) can reduce severe itching in 10 children with a rare genetic skin condition called epidermolysis bullosa. The children took CBD syrup three times a day for a month. Researchers measured itch, pain, sleep, and quality of life before and …

Phase 2 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Symptom relief

Last updated Jun 27, 2026 09:10 UTC

Junctional epidermolysis bullosa

Where it sits in the disease tree

CBD oil may soothe itch in kids with rare skin disease