Isolated short stature
MONDO:1010112A disease characterized by the height of an individual two standard deviations below the corresponding mean height for a given age, sex and population group with no known cause.
Also known as: idiopathic short stature
16 clinical trials for this condition and its sub-types, 16 tagged with Isolated short stature itself.
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Weekly shot could replace daily growth hormone for kids
Disease control Recruiting nowThis phase 3 trial compares a once-weekly growth hormone injection (lonapegsomatropin) to a daily one (somatropin) in 186 prepubertal children with growth failure due to Turner syndrome, SHOX deficiency, being small for gestational age, or idiopathic short stature. The goal is to…
Phase 3 • Sponsor: Ascendis Pharma A/S • Aim: Disease control
Last updated Sep 04, 2026 00:00 UTC
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New hope for short kids: experimental drug takes on growth hormone
Disease control Recruiting nowThis study tests a drug called vosoritide in 100 children with idiopathic short stature (short height with no known cause). The goal is to see if vosoritide can safely improve growth compared to standard growth hormone. Participants will receive either vosoritide or growth hormon…
Phase 2 • Sponsor: BioMarin Pharmaceutical • Aim: Disease control
Last updated Jun 27, 2026 12:37 UTC
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Weekly shot could replace daily needles for short stature kids
Disease control Recruiting nowThis study tests if a once-weekly injection of somatrogon works as well as a daily growth hormone shot for children with short stature. It includes 254 children born small for their age or with no clear cause for their short height. The goal is to see if the weekly option can imp…
Phase 3 • Sponsor: Rabin Medical Center • Aim: Disease control
Last updated Jun 27, 2026 12:26 UTC
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Weekly shot could replace daily needles for short kids
Disease control Recruiting nowThis study tests a new growth hormone medicine (inpegsomatropin) given once a week compared to the standard daily growth hormone shot. About 300 children with idiopathic short stature (short for no known medical reason) will receive either the weekly or daily injection for one ye…
Phase 3 • Sponsor: Xiamen Amoytop Biotech Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 11:01 UTC
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Weekly growth hormone shot tested in thousands of kids
Disease control Recruiting nowThis study is tracking 2,600 Chinese children with growth disorders who are receiving a long-acting growth hormone injection. The goal is to see how well it works and how safe it is over the long term in real-world settings. Researchers will measure changes in height and look for…
Sponsor: Beijing Children's Hospital • Aim: Disease control
Last updated Jun 26, 2026 14:04 UTC
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Growth hormone treatment under Long-Term watch in thousands of children
Knowledge-focused Recruiting nowThis study tracks the long-term safety and effectiveness of the growth hormone treatment Growtropin-II in children with short stature. It includes up to 5,000 children with growth hormone deficiency, idiopathic short stature, Turner syndrome, or those born small for gestational a…
Sponsor: Dong-A ST Co., Ltd. • Aim: Knowledge-focused
Last updated Jul 23, 2026 00:00 UTC
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New study aims to unlock growth secrets in short children
Knowledge-focused Recruiting nowThis study will follow 300 children with idiopathic short stature (ISS) — meaning they are shorter than expected for no known medical reason. Researchers will measure their height, weight, and other health factors over time to create a detailed picture of natural growth. The goal…
Sponsor: BioMarin Pharmaceutical • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:03 UTC
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Scientists hunt for hidden genes behind unexplained short stature
Knowledge-focused Recruiting nowThis study aims to find out how many children with very short height have no known medical cause, and then search for genetic reasons in a small group. Researchers will evaluate 200 children aged 4 to 18 using a team of specialists. The goal is to better understand why some child…
Sponsor: University Hospital, Montpellier • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC