Invasive lobular breast carcinoma
MONDO:0005051An infiltrating lobular adenocarcinoma of the breast. The malignant cells lack cohesion and are arranged individually or in a linear manner (Indian files), or as narrow trabeculae within the stroma. The malignant cells are usually smaller than those of ductal carcinoma, are less pleomorphic, and have fewer mitotic figures.
Also known as: lobular carcinoma, lobular carcinoma (morphologic abnormality), lobular carcinoma NOS (morphologic abnormality), lobular carcinoma of the breast, classic invasive lobular carcinoma, infiltrating lobular adenocarcinoma, infiltrating lobular breast carcinoma, infiltrating lobular carcinoma of breast
2837 clinical trials for this condition and its sub-types, 30 tagged with Invasive lobular breast carcinoma itself.
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Which hormone drug best halts lobular breast cancer growth?
Disease control CompletedThis phase 2 trial compares three hormone therapies—fulvestrant, anastrozole, and tamoxifen—in women with invasive lobular breast cancer, a subtype that is often treated the same as more common breast cancers despite limited evidence. Participants take one of the drugs for about …
Phase 2 • Sponsor: Priscilla McAuliffe • Aim: Disease control
Last updated Aug 09, 2026 00:00 UTC
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New drug combo shows promise for rare breast cancer
Disease control CompletedThis study tested a combination of two drugs, crizotinib and fulvestrant, in 33 people with advanced lobular breast cancer that had lost a protein called E-cadherin. It also tested crizotinib alone in people with diffuse gastric cancer, triple-negative lobular breast cancer, or o…
Phase 2 • Sponsor: Royal Marsden NHS Foundation Trust • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC
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Tiny study sheds light on rare male breast cancer
Knowledge-focused CompletedThis completed study looked at the medical records of 8 men diagnosed with breast cancer at Methodist Health System. Researchers wanted to understand their demographics, how their disease progressed, and what complications they faced. Because male breast cancer is very rare, this…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC