Intracranial thrombosis

This trial tests whether adding tocilizumab, an anti-inflammatory drug, to standard blood thinners improves recovery in people with acute cerebral venous thrombosis, a type of stroke caused by a blood clot in the brain's veins. Researchers will give 80 adults either a single infu…

This study tests whether a newer clot-dissolving drug (tenecteplase) works better than the standard drug (alteplase) when given before a mechanical procedure to remove a large blood clot from the brain. About 850 adults who have had a severe stroke within the last 4.5 hours will …

This study tests whether adding batroxobin, a snake venom enzyme that dissolves clots, to standard blood thinners helps people with acute cerebral venous thrombosis (a rare stroke caused by a clot in a brain vein). Seventy-two adults will be randomly assigned to receive either st…

Researchers are testing a radioactive tracer called 18F/68Ga-GP1 that binds to a protein found on blood clots. Adults with suspected, newly diagnosed, or previously treated thrombi receive one intravenous injection and then undergo PET/CT or MRI imaging. The study measures how mu…

This study is a long-running registry that collects detailed health information from all stroke and dementia patients in Erlangen, Germany. It aims to understand how these diseases develop and affect people over time, regardless of age or severity. Participants are followed for l…

This study is a registry that gathers medical information from up to 40,000 people who have had surgery for stroke, brain aneurysm, or other brain blood vessel problems. Researchers will look at this data to find patterns that help predict recovery and compare different treatment…