Intervertebral disk degenerative disorder

This study tests a single injection of a drug called AGA111 given directly into the spine during back fusion surgery for people with degenerative disc disease. The goal is to see if it helps the bones heal together more successfully and improves pain and function. About 412 adult…

This study tested a special bone graft material (MatriBONE mixed with the patient's own bone marrow) for spinal fusion surgery in people with painful degenerative back problems. The goal was to see how well the bones fused together after 12 months. However, the trial was stopped …

This study looked at a disc replacement device called CerPass for people with a damaged disc in their neck. It aimed to see if the device could reduce pain and improve movement without needing further surgery. Only 2 people joined before the study was stopped early, so results ar…

This study aimed to compare a man-made bone graft material called Virtuos against using the patient's own bone for lumbar spine fusion surgery in people with degenerative disc disease. The goal was to see if Virtuos could achieve similar fusion rates at 12 and 24 months. However,…

This study looked at the VERTICALE Cervical System, a device used to stabilize the spine during surgery. Researchers planned to track neck disability in patients with conditions like degenerative disc disease or trauma. Only 4 patients were enrolled before the study was terminate…

This study was a registry that planned to follow 234 adults undergoing spine fusion surgery for conditions like spinal stenosis and degenerative disc disease. Researchers aimed to compare different surgical techniques and track long-term outcomes, including pain, function, and wh…