Interstitial lung disease
MONDO:0015925A diverse group of lung diseases that affect the lung parenchyma. They are characterized by an initial inflammation of pulmonary alveoli that extends to the interstitium and beyond leading to diffuse pulmonary fibrosis. Interstitial lung diseases are classified by their etiology (known or unknown causes), and radiological-pathological features.
Also known as: ILD, interstitial lung disease
729 clinical trials for this condition and its sub-types, 257 tagged with Interstitial lung disease itself.
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Sub-types of Interstitial lung disease
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Idiopathic pulmonary fibrosis 202 trials
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Interstitial lung disease specific to childhood 5 trials · 163 incl. sub-types
5 sub-types
- Primary interstitial lung disease specific to childhood 45 trials · 156 incl. sub-types Sub-types →
- Hermansky-Pudlak syndrome with pulmonary fibrosis 0 trials · 1 incl. sub-types Sub-types →
- Niemann-Pick disease type B 1 trial
- Familial hypocalciuric hypercalcemia 0 trials · 1 incl. sub-types Sub-types →
- Congenital emphysematous lung disease due to Filamin A loss-of-function variant 0 trials
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Pulmonary fibrosis 140 trials · 143 incl. sub-types
6 sub-types
- Tuberculous fibrosis of lung 3 trials
- Pulmonary fibrosis and/or bone marrow failure, telomere-related 1 trial Sub-types →
- Diffuse pulmonary fibrosis 0 trials
- Graphite pneumoconiosis 0 trials
- Localized pulmonary fibrosis 0 trials
- Postinflammatory pulmonary fibrosis 0 trials
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Bronchiolitis obliterans syndrome 42 trials · 44 incl. sub-types
2 sub-types
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Hypersensitivity pneumonitis 25 trials · 30 incl. sub-types
14 sub-types
- Fibrotic hypersensitivity pneumonitis 9 trials
- Ventilation pneumonitis 2 trials
- Bird fancier's lung 1 trial
- Non-fibrotic hypersensitivity pneumonitis 1 trial
- Bagassosis 0 trials
- Cork-handlers' disease 0 trials
- Farmer's lung disease 0 trials
- House allergic alveolitis 0 trials
- Hypersensitivity pneumonitis, familial 0 trials
- Idiopathic chronic eosinophilic pneumonia 0 trials
- Malt worker's lung 0 trials
- Maple bark strippers' lung 0 trials
- Mushroom workers' lung 0 trials
- Sick building syndrome 0 trials
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Secondary pulmonary hemosiderosis 0 trials · 30 incl. sub-types
1 sub-type
- Heiner syndrome 30 trials
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Radiation pneumonitis 20 trials
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Interstitial lung disease specific to adulthood 0 trials · 20 incl. sub-types
2 sub-types
- Pulmonary sarcoidosis 20 trials
- Langerhans cell histiocytosis specific to adulthood 0 trials Sub-types →
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Pneumoconiosis 5 trials · 13 incl. sub-types
14 sub-types
- Asbestosis 3 trials
- Pulmonary hemosiderosis 2 trials Sub-types →
- Silicosis 2 trials Sub-types →
- Anthracosis 1 trial
- Byssinosis 1 trial
- Caplan syndrome 0 trials
- Anthracosilicosis 0 trials
- Baritosis 0 trials
- Chronic beryllium disease 0 trials
- Graphite pneumoconiosis 0 trials
- Mixed dust pneumoconiosis 0 trials
- Mixed mineral dust pneumoconiosis 0 trials Sub-types →
- Pneumoconiosis due to talc 0 trials
- Slate pneumoconiosis 0 trials
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Inherited interstitial lung disease 5 trials · 11 incl. sub-types
13 sub-types
- Interstitial lung disease 2 2 trials
- Hermansky-Pudlak syndrome with pulmonary fibrosis 0 trials · 1 incl. sub-types Sub-types →
- Niemann-Pick disease type B 1 trial
- Rajab interstitial lung disease with brain calcifications 0 trials · 1 incl. sub-types Sub-types →
- Familial hypocalciuric hypercalcemia 0 trials · 1 incl. sub-types Sub-types →
- Pulmonary fibrosis and/or bone marrow failure, telomere-related 1 trial Sub-types →
- Lane Hamilton syndrome 0 trials
- SFTPC-related interstitial lung disease 0 trials
- Alveolar capillary dysplasia with misalignment of pulmonary veins 0 trials
- Hypersensitivity pneumonitis, familial 0 trials
- Interstitial lung disease 1 0 trials
- Interstitial lung disease due to ABCA3 deficiency 0 trials
- Lung fibrosis-immunodeficiency-46,XX gonadal dysgenesis syndrome 0 trials
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Isolated pulmonary capillaritis 0 trials
Most studied deeper sub-types
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Experimental drug aims to help COVID survivors breathe easier
Disease control Stopped earlyThis study tested a drug called deupirfenidone (LYT-100) in 185 adults who had breathing problems after a serious COVID-19 infection. Participants took either the drug or a placebo for several weeks to see if it improved their ability to walk. The trial was stopped early, so the …
Phase 2 • Sponsor: PureTech • Aim: Disease control
Last updated Jun 27, 2026 14:03 UTC
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Lung disease drug trial in kids halted early
Disease control Stopped earlyThis study tested whether hydroxychloroquine could help children with a rare lung condition called interstitial lung disease. About 35 children were planned to take either the drug or a placebo to see if their oxygen levels or breathing improved. The trial was stopped early, so r…
Phase 2 • Sponsor: Matthias Griese • Aim: Disease control
Last updated Jun 27, 2026 08:00 UTC
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Lung disease drug tested in rare muscle condition – trial cut short
Disease control Stopped earlyThis study tested the drug nintedanib (Ofev) in 11 people with myositis-related interstitial lung disease, a condition where lung scarring occurs alongside muscle inflammation. The goal was to see if the drug is safe and tolerable when added to standard immune-suppressing treatme…
Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre • Aim: Disease control
Last updated Jun 26, 2026 13:17 UTC
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New study tracks lung function and symptoms in fibrosis patients on nintedanib
Knowledge-focused Stopped earlyThis study looked at 88 adults with connective tissue disease-related lung scarring who were prescribed nintedanib. Researchers measured changes in lung function and tracked cough and breathlessness using a questionnaire over 24 months. The goal was to see if improvements in lung…
Sponsor: Boehringer Ingelheim • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Lung cancer study aims to predict dangerous lung inflammation
Knowledge-focused Stopped earlyThis study followed 83 people with advanced non-small cell lung cancer who were starting standard treatments. The goal was to collect information to help develop a digital tool that can spot early signs of pneumonitis/ILD, a serious lung inflammation that can occur as a side effe…
Sponsor: AstraZeneca • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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New lung camera could replace needle biopsies
Knowledge-focused Stopped earlyThis study aimed to see if a tiny camera on a thin tube (bronchoscopy) could help doctors diagnose diffuse lung diseases without needing a surgical lung biopsy. The camera takes live microscopic images of the air sacs. The study was stopped early, but it involved 38 adults with c…
Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC
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Tiny study on drug monitoring in scleroderma ends early
Knowledge-focused Stopped earlyThis study aimed to see if measuring the amount of mycophenolic acid in the blood could help doctors adjust the dose of mycophenolate mofetil (MMF) to better treat skin and lung problems in people with systemic sclerosis. Only 2 patients were enrolled before the study was termina…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:32 UTC