Inherited Creutzfeldt-Jakob disease
MONDO:0007403Inherited or familial Creutzfeldt-Jakob disease (fCJD) is a very rare form of genetic prion disease characterized by typical CJD features (rapidly progressive dementia, personality/behavioral changes, psychiatric disorders, myoclonus, and ataxia) with a genetic cause and sometimes a family history of dementia.
Also known as: Creutzfeldt-Jakob disease, variant, resistance to, hereditary Creutzfeldt Jacob disease, inherited CJD, CJD, Creutzfeldt-Jakob disease, Creutzfeldt-Jakob disease, Heidenhain variant, Creutzfeldt-Jakob disease, familial, Creutzfeldt-Jakob disease, sporadic
17 clinical trials for this condition and its sub-types, 5 tagged with Inherited Creutzfeldt-Jakob disease itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →-
Could an HIV drug extend life in Creutzfeldt-Jakob disease?
Disease control Recruiting nowThis study tests whether efavirenz, a drug used for HIV, can help people with Creutzfeldt-Jakob disease (CJD) live longer. CJD is a rare, rapidly fatal brain disorder. The trial will enroll 246 adults and randomly assign them to receive either efavirenz or a placebo. The main goa…
Phase 3 • Sponsor: Xuanwu Hospital, Beijing • Aim: Disease control
Last updated Sep 05, 2026 00:00 UTC
-
New study seeks to sharpen Alzheimer's diagnosis with simple tests
Diagnosis Recruiting nowThis study aims to find the best cutoff values for key Alzheimer's-related proteins in spinal fluid and blood to improve diagnostic accuracy. Researchers will compare results from Alzheimer's patients, those with mild memory problems, people with other dementias, and healthy olde…
Sponsor: Capital Medical University • Aim: Diagnosis
Last updated Jun 27, 2026 12:00 UTC
-
Simple blood test could revolutionize Alzheimer's diagnosis
Diagnosis Recruiting nowThis study is testing a new blood test called the AD-seeds-detector that looks for specific protein clumps linked to Alzheimer's disease. Researchers will compare the test results from 1,500 people aged 55-75, including those with Alzheimer's, other dementias, and healthy individ…
Sponsor: Capital Medical University • Aim: Diagnosis
Last updated Jun 27, 2026 12:00 UTC
-
Scientists hunt for clues to predict rare brain disease before symptoms strike
Knowledge-focused Recruiting nowThis study aims to find biological markers in spinal fluid and blood that could signal the start of prion disease before symptoms appear. Researchers will follow 150 people who carry a genetic mutation for prion disease, along with family members and healthy volunteers. Participa…
Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Aug 15, 2026 00:00 UTC