Infiltrating bladder urothelial carcinoma sarcomatoid variant
MONDO:0004278An invasive transitional cell carcinoma of the bladder that exhibits spindle cell sarcomatoid features.
Also known as: sarcomatoid carcinoma of the urinary bladder, infiltrating bladder urothelial carcinoma sarcomatoid variant, infiltrating bladder urothelial carcinoma, sarcomatoid variant with heterologous elements, infiltrating bladder urothelial carcinoma, sarcomatoid variant without heterologous elements
2766 clinical trials for this condition and its sub-types, 5 tagged with Infiltrating bladder urothelial carcinoma sarcomatoid variant itself.
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Immunotherapy combo shows promise for bladder cancer patients unable to get chemo
Disease control OngoingThis early-phase trial is testing whether giving two immunotherapy drugs (durvalumab and tremelimumab) before surgery can help patients with aggressive bladder cancer who cannot take standard chemotherapy. The study involves 54 participants and primarily looks at safety and how t…
Early phase 1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Sep 16, 2026 00:00 UTC
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New drug cocktail shows promise for Hard-to-Treat urinary cancers
Disease control OngoingThis early-phase study tests a combination of two or three drugs (cabozantinib, nivolumab, and sometimes ipilimumab) in people with advanced genitourinary cancers that have spread. The main goals are to find the safest doses and understand side effects. About 152 adults with vari…
Phase 1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Sep 12, 2026 00:00 UTC
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New drug combo targets Hard-to-Treat bladder cancer
Disease control OngoingThis study tests a combination of two drugs, pemetrexed and avelumab, in people with a specific type of advanced bladder cancer that lacks a protein called MTAP. The goal is to see if this treatment can shrink or control the cancer. About 18 participants who have already tried ch…
Phase 2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jul 18, 2026 00:00 UTC
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New triple therapy for bladder cancer shows promise in early trial
Disease control OngoingThis early-phase study tests a combination of three drugs (tremelimumab, durvalumab, and belinostat) in people with advanced bladder cancer that has spread or cannot be removed surgically. The main goal is to find the safest dose and understand side effects. About 9 adults who ha…
Phase 1 • Sponsor: University of Utah • Aim: Disease control
Last updated Jun 27, 2026 12:31 UTC