Immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome

MONDO:0010580

Immunodysregulation - polyendocrinopathy - enteropathy - X-linked (IPEX) syndrome is a severe congenital systemic autoimmune disease characterized by refractory diarrhea, endocrinopathies, cutaneous involvement, and infections.

Also known as: DMSD, IDDM-secretory diarrhea syndrome, IDDM-secretory diarrhoea syndrome, IPEX, X linked polyendocrinopathy, X-linked autoimmunity-allergic dysregulation syndrome, XLAAD, XPID

48 clinical trials for this condition and its sub-types, 10 tagged with Immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome itself.

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Where it sits in the disease tree

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Part of

↑ Hereditary disease (18187) ↑ Syndromic disease (7133) ↑ Hypersensitivity reaction disease (1022) ↑ Autoimmune disorder of endocrine system (925) ↑ Polyendocrinopathy (81) ↑ Autoimmune enteropathy (11)

Including sub-types (48) Tagged with Immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome (10)

Trials to join now! 19 Not yet recruiting 10 Not yet finished but already full! 7 Completed 11 Terminated 1

Biopsy tolerance study ends early – what we know

Knowledge-focused Stopped early

This study aimed to understand how well patients tolerate biopsies for autoimmune diseases and whether they feel properly informed. It planned to enroll 505 people but was terminated early. The results may help improve patient experience with these common procedures.

Sponsor: University Hospital, Brest • Aim: Knowledge-focused

Last updated Jun 28, 2026 00:00 UTC

Immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome

Where it sits in the disease tree

Biopsy tolerance study ends early – what we know