Idiopathic pulmonary arterial hypertension
MONDO:0001999A sporadic form of pulmonary arterial hypertension (PAH) characterized by elevated pulmonary arterial resistance leading to right heart failure. IPAH is progressive and potentially fatal and not associated with an underlying condition or family history of PAH. The etiology is unknown.
Also known as: IPAH, idiopathic pulmonary arterial hypertension, primary pulmonary arterial hypertension, primary pulmonary hypertension
64 clinical trials for this condition and its sub-types, 15 tagged with Idiopathic pulmonary arterial hypertension itself.
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Can a smartphone app keep heart failure patients out of the hospital?
Disease control Stopped earlyResearchers are testing a mobile app designed to help people with heart failure manage their condition after leaving the hospital. The app sends personalized messages about low-sodium food choices and alerts based on daily symptom reports. The trial enrolls 62 adults recently hos…
Phase 3 • Sponsor: University of Michigan • Aim: Disease control
Last updated Sep 19, 2026 00:00 UTC
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Heart drug study halted early: limited data on right heart changes
Disease control Stopped earlyThis study looked at whether the drug riociguat could improve right heart size and function in people with two types of pulmonary hypertension (PAH and CTEPH). It planned to enroll 30 adults, but was terminated early, so results are limited. The goal was to use echocardiograms to…
Phase 4 • Sponsor: Heidelberg University • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Early-Stage lung blood pressure drug trial halted
Disease control Stopped earlyThis study tested the drug riociguat in people with early pulmonary vascular disease, a condition where blood vessels in the lungs narrow, making the heart work harder. The trial included 35 adults with connective tissue disease or an inherited form. Participants received either …
Phase 2 • Sponsor: Heidelberg University • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC
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A wearable vest that listens to the lungs: a new hope for heart failure?
Knowledge-focused Stopped earlyThis study tests a wearable device called the ADI Cardio Pulmonary Monitoring (CPM) system, designed to track heart failure signs at home. The goal is to see if the device can be easily used by patients and whether its measurements—like breathing rate and chest fluid levels—match…
Sponsor: Analog Device, Inc. • Aim: Knowledge-focused
Last updated Aug 21, 2026 00:00 UTC