Idiopathic CD4 lymphocytopenia

A rare primary immunodeficiency disorder characterized by persistent CD4 T-cell lymphopenia (less than 300 cells/B5L on multiple occasions) not associated with any other underlying primary or secondary immune deficiency. Patients typically present opportunistic infections (with cryptococcal, mycobacterial, candidal, varicella zoster virus infections and progressive multifocal leukoencephalopathy being the most prevalent), malignancies (mainly lymphoproliferative disorders), or autoimmune disorders. Some individuals are asymptomatic and incidentally diagnosed.

Also known as: immunodeficiency type 13, ICL, IMD13, idiopathic CD4 positive T-lymphocytopenia, idiopathic Cd4 lymphopenia, immunodeficiency 13

7 clinical trials for this condition and its sub-types, 7 tagged with Idiopathic CD4 lymphocytopenia itself.