Ichthyosis, congenital, autosomal recessive 12

MONDO:0015018

Any autosomal recessive congenital ichthyosis in which the cause of the disease is a mutation in the CASP14 gene.

Also known as: ARCI12, ichthyosis, congenital, autosomal recessive 12, ichthyosis, congenital, autosomal recessive 12; ARCI12, ichthyosis, congenital, autosomal recessive type 12

3 clinical trials for this condition and its sub-types, 0 tagged with Ichthyosis, congenital, autosomal recessive 12 itself.

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Where it sits in the disease tree

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↑ Autosomal recessive congenital ichthyosis (10)

Including sub-types (3) Tagged with Ichthyosis, congenital, autosomal recessive 12 (0)

Not yet finished but already full! 1 Completed 1 Terminated 1

New ointment shows promise for rare skin condition

Disease control Completed

This Phase 3 study tested an ointment called TMB-001 in 153 people aged 6 and older with X-linked or ARCI ichthyosis, conditions that cause dry, scaly, and cracked skin. Participants applied the ointment or a placebo daily for 12 weeks, with some continuing for maintenance. The g…

Phase 3 • Sponsor: LEO Pharma • Aim: Disease control

Last updated Jun 27, 2026 12:36 UTC

Ichthyosis, congenital, autosomal recessive 12

Where it sits in the disease tree

New ointment shows promise for rare skin condition