Hypoalphalipoproteinemia
MONDO:0017773A metabolic disorder characterized by deficiency of high density (alpha) lipoprotein in the blood.
7 clinical trials for this condition and its sub-types, 1 tagged with Hypoalphalipoproteinemia itself.
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Sub-types of Hypoalphalipoproteinemia
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LCAT deficiency 1 trial · 4 incl. sub-types
2 sub-types
- Norum disease 2 trials
- Fish eye disease 1 trial
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Apolipoprotein A-I deficiency 0 trials · 2 incl. sub-types
2 sub-types
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Tangier disease 0 trials
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Apolipoprotein A-II deficiency 0 trials
Most studied deeper sub-types
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One patient gets experimental enzyme to fight rare kidney disease
Disease control CompletedThis study tested an artificial version of the LCAT enzyme (ACP-501) in one person with familial LCAT deficiency, a rare genetic condition that leads to low 'good' cholesterol and kidney failure. The participant received several infusions of the drug over weeks, with regular bloo…
Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Disease control
Last updated Sep 18, 2026 00:00 UTC
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Could a 5:2 diet melt fat from your liver?
Disease control CompletedThis study looked at whether an 8-week 5:2 intermittent fasting diet could help people with fatty liver disease. Eighty adults with excess liver fat followed the diet, eating normally for 5 days and restricting calories to 500 kcal on 2 non-consecutive days each week. Researchers…
Sponsor: Beijing Chao Yang Hospital • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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Will breakfast change how this diabetes drug works?
Knowledge-focused CompletedThis early-stage trial in 28 healthy adults tests whether eating a meal changes how the body absorbs a single tablet containing three diabetes medicines (gemigliptin, dapagliflozin, and metformin). Participants take the pill once while fasting and once after a meal, and researche…
Phase 1 • Sponsor: LG Chem • Aim: Knowledge-focused
Last updated Sep 12, 2026 00:00 UTC
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Scientists probe fat particles to unlock heart disease secrets
Knowledge-focused CompletedThis study looked at how fat-carrying particles called lipoproteins work in healthy people and those with high cholesterol or other lipid disorders. Researchers injected tiny, safe amounts of radioactive lipoproteins to track them in the body. The goal was to better understand ho…
Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Knowledge-focused
Last updated Sep 10, 2026 00:00 UTC