Hypertrophic pyloric stenosis
MONDO:0001560An abnormality characterized by thickening of the muscle in the wall of the pylorus. It results in the narrowing of the pyloric channel. The overlying mucosa may appear hypertrophic as well. Clinical signs and symptoms appear early in life and include projectile vomiting and dehydration.
Also known as: IHPS, congenital Hypertrophy of the pylorus, congenital constriction of the pylorus, congenital hypertrophic pyloric stenosis, congenital pyloric stenosis, congenital stricture of the pylorus, infantile Hypertrophy of the pylorus, infantile constriction of the pylorus
18 clinical trials for this condition and its sub-types, 16 tagged with Hypertrophic pyloric stenosis itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Hypertrophic pyloric stenosis
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6 sub-types
- Intellectual disability-hypotonia-brachycephaly-pyloric stenosis-cryptorchidism syndrome 0 trials
- Pyloric stenosis, infantile hypertrophic, 1 0 trials
- Pyloric stenosis, infantile hypertrophic, 2 0 trials
- Pyloric stenosis, infantile hypertrophic, 3 0 trials
- Pyloric stenosis, infantile hypertrophic, 4 0 trials
- Pyloric stenosis, infantile hypertrophic, 5 0 trials
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Can a Macrophage-Targeting drug supercharge CAR-T therapy?
Disease control Not yet recruitingThis trial tests whether adding a drug called axatilimab to standard CAR-T cell therapy can improve outcomes for people with high-risk large B-cell lymphomas. Axatilimab works by conditioning macrophages, a type of immune cell, to potentially help the CAR-T cells fight cancer mor…
Phase 1 • Sponsor: Northside Hospital, Inc. • Aim: Disease control
Last updated Jun 27, 2026 13:07 UTC
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New hope for rare lymphoma: drug combo targets tough cancer
Disease control Not yet recruitingThis study tests whether adding brentuximab vedotin to standard chemotherapy (R-CHP) works better for people newly diagnosed with a rare, aggressive lymphoma linked to the Epstein-Barr virus. About 25 adults will receive the combination and be followed for 2 years to see if the c…
Phase 2 • Sponsor: The First Affiliated Hospital with Nanjing Medical University • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
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New imaging agent aims to light up hidden tumors
Diagnosis Not yet recruitingThis early-stage study will test a new radioactive tracer called [89Zr]DFO-YS5 in 40 people with nerve sheath tumors, bladder cancer, or other advanced solid tumors. The tracer is designed to bind to cancer cells and show up on PET scans, potentially making tumors easier to see. …
Phase 1 • Sponsor: Robert Flavell, MD, PhD • Aim: Diagnosis
Last updated Jun 27, 2026 14:02 UTC
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One-Click autofocus could speed up stomach scopes
Knowledge-focused Not yet recruitingThis study tests a new one-click autofocus system for magnifying endoscopy, which uses computer vision to automatically focus the camera during stomach exams. Researchers will compare it to the standard manual focus method in 93 patients with stomach diseases. The goal is to see …
Sponsor: Shandong University • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC