Hyperthyroidism
MONDO:0004425Overactivity of the thyroid gland resulting in overproduction of thyroid hormone and increased metabolic rate. Causes include diffuse hyperplasia of the thyroid gland (Graves' disease), single nodule in the thyroid gland, and thyroiditis. The symptoms are related to the increased metabolic rate and include weight loss, fatigue, heat intolerance, excessive sweating, diarrhea, tachycardia, insomnia, muscle weakness, and tremor.
Also known as: overactive thyroid
70 clinical trials for this condition and its sub-types, 27 tagged with Hyperthyroidism itself.
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Sub-types of Hyperthyroidism
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Primary hyperthyroidism 1 trial · 59 incl. sub-types
3 sub-types
- Graves disease 53 trials Sub-types →
- Toxic multinodular goitre 7 trials
- Toxic thyroid adenoma 2 trials
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Toxic diffuse goiter 0 trials · 53 incl. sub-types
1 sub-type
- Graves disease 53 trials Sub-types →
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Thyrotoxicosis 2 trials
1 sub-type
- Neonatal thyrotoxicosis 0 trials
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Generalized resistance to thyroid hormone 1 trial · 2 incl. sub-types
6 sub-types
- Thyroid hormone resistance, generalized, autosomal dominant 2 trials
- Athyreosis 0 trials
- Thyroid ectopia 0 trials
- Thyroid hemiagenesis 0 trials
- Thyroid hormone resistance, generalized, autosomal recessive 0 trials
- Thyroid hypoplasia 0 trials
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Secondary hyperthyroidism 0 trials · 2 incl. sub-types
2 sub-types
- TSH producing pituitary tumor 0 trials · 2 incl. sub-types Sub-types →
- Hypothalamic hyperthyroidism 0 trials
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Familial gestational hyperthyroidism 0 trials
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Thyroid crisis 0 trials
Most studied deeper sub-types
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Brain fatigue after thyroid disease: immune system may be to blame
Knowledge-focused Stopped earlyThis study investigates why some people with Graves' disease continue to feel mentally fatigued even after their thyroid levels return to normal. Researchers will compare blood and spinal fluid from 180 participants—60 with mental fatigue, 60 without, and 60 healthy controls—to f…
Sponsor: Vastra Gotaland Region • Aim: Knowledge-focused
Last updated Sep 16, 2026 00:00 UTC
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Could a common virus trigger thyroid troubles?
Knowledge-focused Stopped earlyThis study investigated whether polyomaviruses (a type of common virus) are found more often in people with autoimmune thyroiditis or goiters. Researchers compared virus presence in blood, urine, and thyroid tissue from 49 patients undergoing thyroid surgery. The goal was to see …
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:07 UTC