Hyperthyroidism
MONDO:0004425Overactivity of the thyroid gland resulting in overproduction of thyroid hormone and increased metabolic rate. Causes include diffuse hyperplasia of the thyroid gland (Graves' disease), single nodule in the thyroid gland, and thyroiditis. The symptoms are related to the increased metabolic rate and include weight loss, fatigue, heat intolerance, excessive sweating, diarrhea, tachycardia, insomnia, muscle weakness, and tremor.
Also known as: overactive thyroid
70 clinical trials for this condition and its sub-types, 27 tagged with Hyperthyroidism itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Part of
Sub-types of Hyperthyroidism
-
Primary hyperthyroidism 1 trial · 59 incl. sub-types
3 sub-types
- Graves disease 53 trials Sub-types →
- Toxic multinodular goitre 7 trials
- Toxic thyroid adenoma 2 trials
-
Toxic diffuse goiter 0 trials · 53 incl. sub-types
1 sub-type
- Graves disease 53 trials Sub-types →
-
Thyrotoxicosis 2 trials
1 sub-type
- Neonatal thyrotoxicosis 0 trials
-
Generalized resistance to thyroid hormone 1 trial · 2 incl. sub-types
6 sub-types
- Thyroid hormone resistance, generalized, autosomal dominant 2 trials
- Athyreosis 0 trials
- Thyroid ectopia 0 trials
- Thyroid hemiagenesis 0 trials
- Thyroid hormone resistance, generalized, autosomal recessive 0 trials
- Thyroid hypoplasia 0 trials
-
Secondary hyperthyroidism 0 trials · 2 incl. sub-types
2 sub-types
- TSH producing pituitary tumor 0 trials · 2 incl. sub-types Sub-types →
- Hypothalamic hyperthyroidism 0 trials
-
Familial gestational hyperthyroidism 0 trials
-
Thyroid crisis 0 trials
Most studied deeper sub-types
-
New drug batoclimab shows promise for Hard-to-Treat Graves' disease
Disease control CompletedThis study tested a drug called batoclimab in 35 adults with Graves' disease whose thyroid hormone levels were still high despite taking standard antithyroid drugs. The goal was to see if batoclimab could help bring those levels back to normal or below over 24 weeks. Batoclimab w…
Phase 2 • Sponsor: Immunovant Sciences GmbH • Aim: Disease control
Last updated Aug 15, 2026 00:00 UTC
-
Foot flex could tame cholesterol and blood sugar
Disease control CompletedThis study tests whether a simple foot exercise called the soleus pushup can improve cholesterol, blood sugar, and hormone levels in people with thyroid problems, high blood pressure, or diabetes. Participants will perform the exercise, and researchers will measure changes in blo…
Sponsor: King Abdullah University Hospital • Aim: Disease control
Last updated Jul 09, 2026 00:00 UTC
-
New hope for thyroid eye disease: drug shows promise in Steroid-Resistant patients
Disease control CompletedThis study looked at whether tocilizumab, a drug that calms the immune system, can help people with active moderate-to-severe thyroid eye disease that did not get better with steroids. Thirty-two adults received the drug every four weeks. Researchers measured improvements in eye …
Sponsor: Medical University of Warsaw • Aim: Disease control
Last updated Jun 27, 2026 13:03 UTC
-
Virtual reality goggles ease pain during thyroid needle biopsy
Symptom relief CompletedThis study tested whether wearing virtual reality glasses during a fine needle biopsy of the thyroid could lower stress and pain in people with hyperthyroidism. 52 patients took part. Researchers measured stress and pain levels using questionnaires and checked vital signs. The go…
Sponsor: Yuzuncu Yil University • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
-
New nerve block combo could cut opioid use after thyroid surgery
Symptom relief CompletedThis study tested whether adding dexmedetomidine to a standard nerve block (superficial cervical plexus block) improves pain control after thyroid surgery. Fifty-eight adults undergoing thyroid surgery were randomly assigned to receive the nerve block with or without dexmedetomid…
Sponsor: Udayana University • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
-
New 3D scan could improve thyroid testing
Knowledge-focused CompletedThis study tested whether a newer 3D imaging method (SPECT/CT) is as accurate as the standard 2D method for measuring how much the thyroid gland takes up a radioactive tracer. 27 people with underactive or overactive thyroids were scanned with both methods. The goal was to see if…
Sponsor: Centre Hospitalier Princesse Grace • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:39 UTC