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New nerve block combo could cut opioid use after thyroid surgery

NCT ID NCT07274670

Symptom relief Sponsor: Udayana University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether adding dexmedetomidine to a standard nerve block (superficial cervical plexus block) improves pain control after thyroid surgery. Fifty-eight adults undergoing thyroid surgery were randomly assigned to receive the nerve block with or without dexmedetomidine. The main goal was to see how long it took before patients needed pain medication and how much opioid painkiller they used in the first 24 hours.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Dexmedetomidine and Bupivacaine
What this could lead to
If it works, this could lead to better pain control and less reliance on opioids after thyroid surgery.
What could go wrong
This is a small, completed trial with only 58 participants. Results may not apply to everyone, and there is a risk of side effects like slow heart rate.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

58 people

The number who actually took part.

Started

Jul 2025

Finished

Nov 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

30 to 59 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients aged 30-59 years. * Patients with ASA physical status classification I-III. * Patients with Body Mass Index (BMI) between 18 and 25 kg/m Exclusion Criteria: * Patients with contraindications for regional anesthesia. * Patients with a history of autoimmune disease. * Presence of infection in the puncture area. * Patients with allergies and contraindications to the use of dexmedetomidine. * Patients on routine medication, including beta-blockers, anti-depressants, or anti-seizure medications. * Prolonged opioid use. * Patients unable to be assessed using the Visual Analogue Scale (VAS) or unable to operate the Patient-Controlled Analgesia (PCA) device. * Patients who refuse to participate in the study.

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Conditions

The condition(s) this trial relates to.

Chronic Pain goiter hyperthyroidism Pain, Postoperative thyroid cancer Thyroid Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Goiter Hyperthyroidism Thyroid cancer

Contacts and locations

Locations

  • Prof. Dr. I.G.N.G Ngoerah Central General Hospital

    Denpasar, Bali, 80114, Indonesia

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