Hypersensitivity reaction disease
MONDO:0000605An immune system disease that has basis in dysregulation of the hypersensitivity reaction, an inflammatory response to an exogenous environmental antigen or an endogenous antigen initiated by the adaptive immune system.
Also known as: allergic reaction, sensitive, sensitivity, hypersensitive, hypersensitivity, hypersensitivity reaction
1022 clinical trials for this condition and its sub-types, 32 tagged with Hypersensitivity reaction disease itself.
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Sub-types of Hypersensitivity reaction disease
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Allergic disease 178 trials · 966 incl. sub-types
12 sub-types
- Atopic eczema 467 trials · 480 incl. sub-types Sub-types →
- Allergic respiratory disease 2 trials · 218 incl. sub-types Sub-types →
- Food allergy 115 trials
- Drug allergy 35 trials
- Eye allergy 2 trials · 20 incl. sub-types Sub-types →
- Atopic IgE-mediated allergic disorder 13 trials
- Venom allergy 12 trials
- Gastrointestinal allergy 0 trials · 5 incl. sub-types Sub-types →
- Alpha-gal syndrome 4 trials
- Allergic otitis media 0 trials Sub-types →
- Latex allergy 0 trials
- Vulvovaginitis, allergic seminal 0 trials
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Anaphylaxis 26 trials · 27 incl. sub-types
2 sub-types
- Exercise-induced anaphylaxis 0 trials · 1 incl. sub-types Sub-types →
- Idiopathic anaphylaxis 1 trial
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Type IV hypersensitivity disease 0 trials · 18 incl. sub-types
3 sub-types
- Autoimmune lymphoproliferative syndrome 11 trials · 12 incl. sub-types Sub-types →
- Cryoglobulinemia 3 trials Sub-types →
- Serum sickness 3 trials
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Hypersensitivity vasculitis 0 trials · 16 incl. sub-types
2 sub-types
- Immunoglobulin A vasculitis 16 trials
- Allergic cutaneous vasculitis 1 trial
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IgE responsiveness, atopic 9 trials
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Type III hypersensitivity disease 3 trials · 6 incl. sub-types
2 sub-types
- Serum sickness 3 trials
- Arthus reaction 0 trials
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Progestogen hypersensitivity 3 trials
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Pseudoallergy 0 trials
1 sub-type
- Drug pseudoallergy 0 trials
Most studied deeper sub-types
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Poop pills may tame severe immunotherapy side effects in cancer patients
Disease control CancelledThis study tests a treatment made from healthy donor stool (MTP-101-C) for cancer patients whose skin or gut side effects from immunotherapy don't get better with steroids. About 30 participants will take the oral capsules to see if the therapy is safe and can calm these side eff…
Phase 2 • Sponsor: Diwakar Davar • Aim: Disease control
Last updated Aug 16, 2026 00:00 UTC
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Brain scans reveal why tourette patients are hypersensitive to everyday stimuli
Knowledge-focused By invitation onlyThis study aims to understand why many people with Tourette syndrome are overly sensitive to everyday sensations like touch or noise. Researchers will monitor brain activity, heart rate, and sweat responses in 50 adults with Tourette syndrome while they experience different sound…
Sponsor: Vanderbilt University Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC