Histoplasmosis
MONDO:0018312A disease caused by the fungus Histoplasma capsulatum. It primarily affects the lungs but can also occur as a disseminated disease that affects additional organs. The acute respiratory disease has symptoms similar to those of a cold or flu and it usually resolves without treatment in healthy individuals. The disseminated form is generally fatal if untreated.
Also known as: Histoplasma caused disease or disorder, Histoplasma disease or disorder, Histoplasma infectious disease, darling disease
7 clinical trials for this condition and its sub-types, 5 tagged with Histoplasmosis itself.
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Sub-types of Histoplasmosis
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Histoplasma capsulatum infectious disease 0 trials · 1 incl. sub-types
3 sub-types
- Histoplasmosis retinitis 1 trial
- African histoplasmosis 0 trials
- Histoplasmosis meningitis 0 trials
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Histoplasma pericarditis 0 trials
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New drug combo could shorten histoplasmosis treatment by half
Disease control Not yet recruitingThis study tests if a single high dose of an antifungal drug works better than the standard daily dose for treating moderate to severe histoplasmosis, a serious lung infection. It also compares a newer oral drug to the standard one, and checks if 6 months of treatment is as good …
Phase 3 • Sponsor: University of Minnesota • Aim: Disease control
Last updated Sep 18, 2026 00:00 UTC
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Can a new pill tame fungal infections when standard drugs fail?
Disease control Not yet recruitingThis Phase 2 trial tests an oral antifungal drug called oteseconazole in adults with dimorphic fungal infections, including coccidioidomycosis, blastomycosis, and histoplasmosis. Participants must already be on antifungal therapy but need a different option because standard first…
Phase 2 • Sponsor: University of Minnesota • Aim: Disease control
Last updated Sep 06, 2026 00:00 UTC
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Prison walls may not stop Animal-Borne diseases
Knowledge-focused Not yet recruitingResearchers are measuring how often five animal-borne infections appear among inmates at the French Guiana Correctional Facility. The study follows newly arrived adults for up to 12 months, testing for Q fever, leptospirosis, Chagas disease, histoplasmosis, and toxoplasmosis. The…
Sponsor: Centre Hospitalier de Cayenne • Aim: Knowledge-focused
Last updated Sep 11, 2026 00:00 UTC