Histiocytosis
MONDO:0002637A morphologic finding indicating tissue infiltration by non-neoplastic or neoplastic histiocytes.
Also known as: histiocytic infiltrate, histiocytic syndrome, histiocytic and dendritic cell neoplasms
75 clinical trials for this condition and its sub-types, 16 tagged with Histiocytosis itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Histiocytosis
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Langerhans cell histiocytosis 40 trials · 41 incl. sub-types
8 sub-types
- Langerhans cell histiocytosis specific to childhood 1 trial Sub-types →
- Langerhans cell histiocytosis specific to adulthood 0 trials Sub-types →
- Eosinophilic granuloma 0 trials Sub-types →
- Hand-Schuller-Christian disease 0 trials
- Multisystem langerhans cell histiocytosis 0 trials
- Pulmonary langerhans cell histiocytosis 0 trials
- Single-system multifocal langerhans cell histiocytosis 0 trials
- Unifocal langerhans cell histiocytosis 0 trials
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Non-Langerhans cell histiocytosis 1 trial · 39 incl. sub-types
15 sub-types
- Niemann-Pick disease 10 trials · 22 incl. sub-types Sub-types →
- Erdheim-Chester disease 14 trials
- Sinus histiocytosis with massive lymphadenopathy 11 trials Sub-types →
- Juvenile xanthogranuloma 4 trials
- Indeterminate dendritic cell tumor 1 trial
- Xanthogranuloma 1 trial Sub-types →
- Benign cephalic histiocytosis 0 trials
- Generalized eruptive histiocytosis 0 trials
- Hereditary progressive mucinous histiocytosis 0 trials
- Multicentric reticulohistiocytosis 0 trials
- Necrobiotic xanthogranuloma 0 trials
- Papular xanthoma 0 trials
- Progressive nodular histiocytosis 0 trials
- Sea-blue histiocyte syndrome 0 trials
- Xanthoma disseminatum 0 trials
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Malignant histiocytosis 3 trials
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ALK+ histiocytosis 0 trials
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Reticulohistiocytic granuloma 0 trials
Most studied deeper sub-types
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Can a targeted pill tame a rare immune disease?
Disease control Not yet recruitingThis phase 2 trial is testing whether the experimental drug luvometinib, taken alone or with the chemotherapy drug cytarabine, can control Langerhans cell histiocytosis—a rare disease where immune cells build up and damage tissues. People aged 10 and older who need systemic treat…
Phase 2 • Sponsor: Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University • Aim: Disease control
Last updated Jul 29, 2026 00:00 UTC
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Heart scans could spot hidden risks in lupus patients
Knowledge-focused Not yet recruitingThis study will follow 1,500 people with lupus or other autoimmune diseases to see if advanced heart scans can predict heart attacks, strokes, or other heart problems. Participants will have one of three types of heart imaging. The goal is to learn if these scans can help doctors…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC
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500 patients to help unlock secrets of rare histiocytosis disorders
Knowledge-focused Not yet recruitingThis study will collect blood, saliva, urine, and stool samples from 500 adults with systemic histiocytosis—a group of rare inflammatory disorders. Researchers aim to identify biomarkers that could improve diagnosis, predict disease progression, and enable less invasive monitorin…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 26, 2026 14:07 UTC