Hilar cholangiocarcinoma
MONDO:0003345A cholangiocarcinoma that arises from the junction, or adjacent to the junction, of the right and left hepatic ducts.
Also known as: Klatskin tumor, Klatskin's tumor, cholangiocarcinoma of hilar portion of hepatic duct, hilar CC, hilar CCA, hilar cholangiocarcinoma, hilar portion of hepatic duct cholangiocarcinoma, hilar cholangiocellular carcinoma
2993 clinical trials for this condition and its sub-types, 36 tagged with Hilar cholangiocarcinoma itself.
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Can a One-Two punch of heat and drainage tame inoperable bile duct cancer?
Disease control CompletedThis trial is testing a personalized treatment for people with inoperable perihilar cholangiocarcinoma, a type of bile duct cancer. The approach combines radiofrequency ablation — using heat to destroy tumor tissue — with complete drainage of bile ducts, guided by both endoscopy …
Sponsor: Clinical Hospital Colentina • Aim: Disease control
Last updated Jul 31, 2026 00:00 UTC
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New chemo combo shows promise for deadly bile duct cancer
Disease control CompletedThis phase 2 trial tested whether adding chemotherapy directly into the liver artery (hepatic arterial infusion) to standard bile duct drainage could help people with advanced perihilar cholangiocarcinoma live longer. The study enrolled 127 adults with inoperable cancer. One grou…
Phase 2 • Sponsor: Peking University • Aim: Disease control
Last updated Jun 27, 2026 08:05 UTC
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New biopsy technique may spot hidden abdominal cancers without major surgery
Diagnosis CompletedThis study looked at how well a special biopsy method called EUS-FNB can diagnose hard-to-reach tumors in the abdomen, such as those near the bile duct or small intestine. Researchers reviewed data from 131 patients who had this procedure over 10 years. The goal was to see if thi…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Diagnosis
Last updated Jun 27, 2026 13:01 UTC
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Which biopsy is best for hilar cancer? new study aims to find out
Diagnosis CompletedThis study compares two ways to get tissue samples from a suspected hilar bile duct cancer: one using an endoscope with ultrasound guidance (EUS-FNA/B) and another using a scope to look directly into the bile ducts (ERCP with or without a special camera). Researchers will check w…
Sponsor: Qilu Hospital of Shandong University • Aim: Diagnosis
Last updated Jun 27, 2026 08:14 UTC
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String-Attached stent may ease bile duct cancer surgery prep
Symptom relief CompletedThis pilot study tested a plastic stent with a retrieval string to drain bile in 40 people with resectable bile duct cancer. The goal was to see if the stent could safely reduce bile buildup before surgery. Researchers measured serious complications and how well the stent worked.
Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) • Aim: Symptom relief
Last updated Jun 27, 2026 12:37 UTC
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Study aims to cut hospital time after liver surgery by looking beyond medicine
Knowledge-focused CompletedThis completed study looked at 3000 patients having liver surgery to see if considering both medical and social factors could reduce how long they stay in the hospital. Researchers tracked things like complications and readmissions. The goal is to find ways to improve recovery an…
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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New 3D method may improve tumor measurement accuracy
Knowledge-focused CompletedThis study looked at 120 adults with breast, pancreatic, or biliary cancer to see if a new 3D measurement method (TDTP-RECIST) is better than the standard way (RECIST 1.1) for tracking tumor shrinkage before surgery. Researchers compared imaging results with actual tumor tissue r…
Sponsor: Shanghai Zhongshan Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC