Hereditary spastic paraplegia 12

Autosomal dominant spastic paraplegia type 12 is a pure form of hereditary spastic paraplegia characterized by a childhood- to adulthood-onset of slowly progressive lower limb spasticity and hyperreflexia of lower extremities, extensor plantar reflexes, distal sensory impairment, variable urinary dysfunction and pes cavus.

Also known as: RTN2 hereditary spastic paraplegia, SPG12, autosomal dominant spastic paraplegia type 12, hereditary spastic paraplegia caused by mutation in RTN2, hereditary spastic paraplegia type 12, spastic paraplegia 12, spastic paraplegia 12, autosomal dominant

2 clinical trials for this condition and its sub-types, 0 tagged with Hereditary spastic paraplegia 12 itself.