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Hereditary spastic paraplegia 11

MONDO:0011445

Any hereditary spastic paraplegia in which the cause of the disease is a mutation in the SPG11 gene.

Also known as: HSP-TCC, Nakamura-Osame syndrome, SPG11, SPG11 hereditary spastic paraplegia, autosomal recessive spastic paraplegia type 11, hereditary spastic paraplegia caused by mutation in SPG11, hereditary spastic paraplegia type 11, spastic paraplegia-intellectual disability-thin corpus callosum syndrome

3 clinical trials for this condition and its sub-types, 1 tagged with Hereditary spastic paraplegia 11 itself.

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Part of

↑ Complex hereditary spastic paraplegia (7)

Including sub-types (3) Tagged with Hereditary spastic paraplegia 11 (1)

Trials to join now! 1

Scientists launch major effort to track rare nerve disease in children

Knowledge-focused Recruiting now

This study collects health information and biological samples from up to 700 people under 30 with early-onset hereditary spastic paraplegia (HSP). Researchers aim to better understand how the disease progresses over time and create a registry for future studies. Participants prov…

Sponsor: Boston Children's Hospital • Aim: Knowledge-focused

Last updated Jun 27, 2026 11:02 UTC

Hereditary spastic paraplegia 11

Where it sits in the disease tree

Scientists launch major effort to track rare nerve disease in children