Hereditary angioedema

MONDO:0019623

Hereditary angioedema (HAE) is a genetic disease characterized by the occurrence of transitory and recurrent subcutaneous and/or submucosal edemas resulting in swelling and/or abdominal pain.

Also known as: HAE, familial angioneurotic edema, familial angioneurotic oedema, hereditary angioedema, hereditary angioneurotic edema, hereditary angioneurotic oedema, hereditary bradykinine-induced angioedema, hereditary non histamine-induced angioedema

61 clinical trials for this condition and its sub-types, 58 tagged with Hereditary angioedema itself.

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Where it sits in the disease tree

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Part of

↑ Hereditary skin disorder (880) ↑ Angioedema (66)

Sub-types of Hereditary angioedema

Hereditary angioedema with C1Inh deficiency 14 trials · 32 incl. sub-types
2 sub-types
- Hereditary angioedema type 1 26 trials
- Hereditary angioedema type 2 26 trials
Hereditary angioedema type 3 2 trials
Hereditary angioedema with normal C1Inh 2 trials
PLG-related hereditary angioedema with normal C1inh 0 trials
Angioedema, hereditary, 4 0 trials
Angioedema, hereditary, 5 0 trials
Angioedema, hereditary, 6 0 trials
Angioedema, hereditary, 7 0 trials
Angioedema, hereditary, 8 0 trials
Hereditary angioedema with normal C1inh not related to F12 or PLG variant 0 trials

Including sub-types (61) Tagged with Hereditary angioedema (58)

Trials to join now! 19 Not yet recruiting 2 Not yet finished but already full! 16 Completed 20 Terminated 1

Could a daily pill stop hereditary angioedema attacks?

Disease control Stopped early

This trial tests whether an experimental oral medication, deucrictibant, can reduce the number of swelling attacks in people with hereditary angioedema (HAE) types I and II. Participants take either a low or high dose of the drug or a placebo for 12 weeks, and then may continue o…

Phase 2 • Sponsor: Pharvaris Netherlands B.V. • Aim: Disease control

Last updated Aug 19, 2026 00:00 UTC

Hereditary angioedema

Where it sits in the disease tree

Could a daily pill stop hereditary angioedema attacks?