Hemorrhagic stroke

This early-phase study tests whether a drug called Tenecteplase (TNK) is safe to inject directly into a brain bleed (intracerebral hemorrhage). Five adults aged 18-80 with large bleeds will receive a single dose during standard surgery. The goal is to see if TNK can dissolve the …

This study tests a smartphone app called StrokeApp designed to support people after a stroke or mini-stroke. The app provides educational content, medication reminders, and tools to track health. Researchers will compare quality of life and other health measures between 500 patie…

This study tests whether a short course of the steroid methylprednisolone can reduce the risk of stroke or death within 30 days after a flow-diverter stent is placed to treat an unruptured brain aneurysm. About 864 adults will be randomly assigned to receive either the steroid or…

This study tests whether a lab-made version of bezoar, called Calculus Bovis Sativus (CBS), can help people recover from a brain hemorrhage. 300 participants will take CBS or natural bezoar pills for 7 days. Researchers will measure recovery using standard stroke scales and brain…

This study will check if an artificial intelligence (AI) system can accurately score stroke severity as well as a trained doctor. About 297 adults with a recent stroke will have their speech and facial movements recorded. The AI will analyze these recordings to produce a G-FAST s…

This study will check if a non-invasive device can accurately detect high pressure inside the skull in 300 adults with traumatic brain injury or stroke. The device uses a sensor placed on the head to measure brain pressure and pulse waves. If successful, it could help doctors mak…

This pilot study tests two non-invasive methods to keep the airways clear in adults who are unconscious or severely ill and need a breathing tube. One method uses a special tube with continuous low-pressure suction, and the other delivers a programmed 'artificial cough' through t…

This study tests a new way to improve vision loss caused by a stroke. It combines low-intensity focused ultrasound (LIFUS) with virtual reality therapy to stimulate the brain's vision areas. The study will enroll 28 adults who had a stroke 6 to 24 months ago and now have partial …

This study compares early task-oriented rehabilitation (practicing daily-life activities) to traditional physiotherapy in 158 adults who had a stroke within the past 48 hours. The goal is to see which approach leads to better motor function and quality of life after 3 months. Par…

This study tests whether an artificial intelligence system can help therapists set better rehab exercises for a robotic arm trainer used by stroke patients. One hundred adults who had a stroke within the last six months will receive either AI-guided or therapist-guided robotic th…

This study tests whether adding occupation-based bilateral arm training (OBBT) to standard therapy helps stroke survivors improve arm movement and daily activities. 150 participants in inpatient rehab will either get OBBT plus standard care or standard care alone for 6 weeks. The…

This study looks at whether patients recovering from a first acute stroke do better in a specialized stroke unit than in a conventional neurology ward. Researchers will follow 140 adults admitted within 48 hours of symptom onset, comparing outcomes like daily independence, disabi…

This study explores why stroke survivors often feel extreme muscle fatigue. Researchers will use a gentle, non-invasive brain stimulation technique called tACS to temporarily change brain activity in 120 stroke survivors. Participants will do leg exercises until tired while their…

This observational study aims to understand how neuromuscular fatigue develops in stroke survivors compared to healthy individuals. Researchers will measure brain activity (EEG) and muscle activity (EMG) in 120 participants while they perform repeated leg exercises until fatigue.…

This study tests whether a program called PEER-HOMEcare is practical and helpful for people recovering from stroke at home. The program involves therapists and family members working together to adapt the home environment and use wearable sensors to track movement. Researchers wi…

This study will test whether mild electrical brain stimulation, combined with physical therapy, changes brain activity in people who had a stroke. Sixty participants will receive either direct or alternating current stimulation during rehab sessions. Researchers will measure bloo…

This study will check how common thinking and memory problems are in people who have had their first stroke. Researchers will evaluate 400 adults aged 18 to 60 within three months of their stroke. The goal is to better understand the impact of stroke on the brain, not to test a n…

This study will test a new robotic and virtual reality system called NeglectARm 3D in 15 people who have spatial neglect after a stroke. The system uses a robot arm and VR headset to measure how well patients notice objects in 3D space. Researchers want to see if the device is ea…

This study will follow 500 people who recently had a stroke or mini-stroke to see how well they stick with cholesterol-lowering treatments like statins and diet changes. Researchers want to learn how many patients reach their LDL cholesterol goals and whether better control reduc…