Hemangioblastoma
MONDO:0016748Hemangioblastoma is a rare, benign, highly vascularized tumor of the central nervous system, most often located in the cerebellum or spinal cord, presenting in adulthood and manifesting with dizziness, nausea, malaise, headache, bladder or bowel dysfunction, numbness, weakness and pain in the upper or lower extremities, and often associated with von Hippel-Lindau disease (VHL). Exceptional cases of hemangioblastoma arising outside of the central nervous system have been reported.
Also known as: angioblastoma, capillary hemangioblastoma, hemangioblastoma, HMBL
1444 clinical trials for this condition and its sub-types, 9 tagged with Hemangioblastoma itself.
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Sub-types of Hemangioblastoma
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Retinal hemangioblastoma 1 trial
1 sub-type
- Isolated retinal racemose hemangioma 0 trials
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Brain stem hemangioblastoma 0 trials
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Cerebellar hemangioblastoma 0 trials
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New hope for rare cancers: immunotherapy drug targets tumors regardless of origin
Disease control Recruiting nowThis study tests the drug nivolumab in people with advanced rare cancers that have a specific marker (PD-L1). The goal is to see if the drug can shrink or control the tumors when other treatments have stopped working. Up to 28 adults will receive treatment for up to 12 months, an…
Phase 2 • Sponsor: Instituto do Cancer do Estado de São Paulo • Aim: Disease control
Last updated Jun 27, 2026 12:08 UTC
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New hope for VHL patients: belzutifan trial targets rare tumor disorder
Disease control Recruiting nowThis study tests the drug belzutifan in 100 people with von Hippel-Lindau (VHL) syndrome, a genetic condition that causes tumors in various organs. Researchers will track how well the drug shrinks tumors and how long it takes for the disease to progress, while also monitoring sid…
Phase 2 • Sponsor: José Claudio Casali da Rocha • Aim: Disease control
Last updated Jun 26, 2026 15:43 UTC
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New brain scan could spot tumors missed by standard MRI
Diagnosis Recruiting nowThis study tests whether a special PET/MRI scan using a radioactive tracer called Ga68-DOTATATE can better detect certain brain tumors (like meningioma) and tell them apart from changes caused by past treatments. About 200 adults with these tumors will get the scan alongside stan…
Phase 4 • Sponsor: Weill Medical College of Cornell University • Aim: Diagnosis
Last updated Jun 27, 2026 07:59 UTC
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New brain tumor labels could guide better treatments
Knowledge-focused Recruiting nowThis study is collecting data from 1,650 people with various brain tumors to see if the updated 2021 WHO classification system helps doctors group patients more accurately and choose better treatments. Researchers will track responses to therapy, survival, and tumor features over…
Sponsor: European Organisation for Research and Treatment of Cancer - EORTC • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC
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New scan could reveal hidden kidney cancer activity
Knowledge-focused Recruiting nowThis study explores whether a special PET/CT scan using a tracer called [18F]PT2385 can detect a protein (HIF2α) that helps kidney cancers grow. About 35 adults with kidney cancer or a genetic condition called VHL syndrome will receive the scan, and results will be compared with …
Phase 1 • Sponsor: Orhan Kemal Oz • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC