Helicobacter pylori infectious disease

Researchers test whether adding black seed oil to a vonoprazan-based triple therapy clears Helicobacter pylori infection better than the standard triple therapy alone. The trial enrolls 90 adults with confirmed H. pylori who have not been treated before. Participants receive eith…

This trial compares three ways to treat Helicobacter pylori, a common stomach infection that can lead to ulcers or cancer. One approach uses genetic testing to pick antibiotics, another uses traditional sensitivity testing, and the third uses a standard fixed combination. The goa…

This study tests two different drug combinations to treat Helicobacter pylori, a stomach bacteria that can cause indigestion. About 66 adults with dyspepsia will receive either a triple therapy (amoxicillin, clarithromycin, esomeprazole) or a quadruple therapy (bismuth, metronida…

This study tests whether adding a natural substance called lignin to the usual antibiotic treatment helps more people get rid of H. pylori infection. About 70 adults with a first-time H. pylori diagnosis will take either lignin or a placebo daily for two weeks, alongside standard…

This study tests a new device called the esophageal string test (EST) to diagnose H. pylori, a stomach bacteria that can cause ulcers and cancer. Participants swallow a capsule with a string inside that collects stomach fluids. Researchers compare the results to standard tests. T…

This trial tests whether routinely screening heart attack patients for H. pylori, a common stomach bacteria, can prevent upper gastrointestinal bleeding. The bacteria can cause ulcers that bleed, especially when patients take blood thinners after a heart attack. Researchers will …

This study was designed to see if treating a common stomach bacteria (H. pylori) along with using a stomach acid drug could prevent ulcers caused by low-dose aspirin. It planned to enroll adults with heart or artery disease who needed long-term aspirin therapy. However, the study…

This study screens 500 adults in South Florida for H. pylori, a stomach infection that can lead to chronic gastritis, ulcers, and gastric cancer. Those who test positive receive free treatment with a three-drug combination (VOQUEZNA® Triple Pak®) for 14 days. The goal is to see i…

This study screens people in South Florida for H. pylori, a stomach infection that can lead to chronic gastritis, ulcers, and even stomach cancer. Those who test positive receive treatment, and the study compares at-home breath testing versus in-person retesting to confirm the in…

This study looks at genetic changes in people with H. pylori infection or stomach cancer to understand how the infection can lead to cancer. Researchers will analyze tissue samples from 110 adults undergoing endoscopy. The goal is to find early warning signs and possible ways to …