Heiner syndrome

This Phase 3 study is testing whether an oral drug called remibrutinib can help people with IgE-mediated allergies to peanuts, cow's milk, or hen's egg tolerate larger amounts of the allergen without symptoms. Adults and adolescents aged 12 to 65 will receive either the drug or a…

This study tests whether giving pasteurized donor human milk to full-term babies of mothers with diabetes during the first five days of life can reduce the number of infants admitted to the neonatal unit for low blood sugar. About 1,444 mothers and their newborns will be randomly…

This study tests modified oral immunotherapy (OIT) protocols for peanut, milk, and egg allergies in 360 participants. The goal is to see if using lower doses or processed allergens can reduce allergic reactions during treatment while still helping people become desensitized to th…

This study tests whether gradually introducing cow's milk in less-heated forms over 12 months helps children with milk allergy develop full tolerance faster than just eating well-cooked milk. About 90 children aged 1-18 who already tolerate heated milk will be split into groups: …

This study compares a hydrolysed rice formula to a standard cow's milk-based formula in 86 infants aged 0-13 months with cow's milk allergy. Over 28 days, researchers will measure growth, digestive comfort, and allergy symptoms to see if the rice formula works just as well. If su…

This study compares two ways of giving oral immunotherapy to children aged 6–16 with milk or egg allergy. One method uses daily increasing doses over a week ('rush'), while the other uses doses every two weeks ('conventional'). The goal is to see which is safer and more effective…

This study tests a new formula made from hydrolyzed rice protein in 104 infants up to 8 months old with cow's milk protein allergy. The goal is to see if it supports normal growth, digestion, and quality of life as well as a standard cow's milk-based formula. Infants will receive…

This study tests whether a special hypoallergenic baby formula is safe for infants and children with cow's milk allergy. About 61 children will try the formula in a controlled setting, then drink it at home for a week. Researchers will watch for allergic reactions and track how m…

This study tests a special infant formula designed for babies with cow's milk protein allergy. The formula includes added prebiotics, probiotics, and a human milk oligosaccharide to help ease allergy symptoms. About 41 infants under 10 months old will use the formula for 4 weeks,…

This study follows 30 children with cow's milk allergy who did not become tolerant after a previous treatment. Researchers will observe whether these children naturally develop tolerance over time without any new intervention. The goal is to better understand the natural course o…

This study looks at children aged 4 to 10 with mild to moderate cow's milk or egg allergies. Researchers want to find biological markers that predict whether a child will naturally outgrow their allergy or benefit from oral immunotherapy (OIT). The goal is to help families and do…

This study looks at children and young people who completed an 18-month oral immunotherapy (OIT) treatment for peanut, egg, or milk allergy 5 to 15 years ago. Researchers want to compare quality of life between those whose allergies went into remission and those whose did not. Pa…

This study compares how well people who report cow milk intolerance digest goat milk versus cow milk. Twenty participants will drink both types of milk on separate days, and researchers will measure digestive discomfort and how nutrients are absorbed. The goal is to see if goat m…