Heart septal defect
MONDO:0002078A congenital disorder characterized by the presence of an abnormal communication between the atria or the ventricles of the heart due to defects in the cardiac septum.
Also known as: Cardiac septal defects, congenital septal defect, holes in the heart
167 clinical trials for this condition and its sub-types, 3 tagged with Heart septal defect itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
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Sub-types of Heart septal defect
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Atrial septal defect 45 trials · 78 incl. sub-types
15 sub-types
- Patent foramen ovale 36 trials
- Atrial septal defect, ostium secundum type 8 trials
- Atrial septal defect 2 1 trial
- Lutembacher syndrome 0 trials
- Atrial septal defect 1 0 trials
- Atrial septal defect 3 0 trials
- Atrial septal defect 4 0 trials
- Atrial septal defect 5 0 trials
- Atrial septal defect 6 0 trials
- Atrial septal defect 7 0 trials
- Atrial septal defect 8 0 trials
- Atrial septal defect 9 0 trials
- Atrial septal defect, coronary sinus type 0 trials
- Atrial septal defect, ostium primum type 0 trials
- Atrial septal defect, sinus venosus type 0 trials
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Ventricular septal defect 24 trials · 26 incl. sub-types
5 sub-types
- Double outlet right ventricle 2 trials · 3 incl. sub-types Sub-types →
- Anterior deviation infundibular septum 0 trials
- Ventricular septal defect 1 0 trials
- Ventricular septal defect 2 0 trials
- Ventricular septal defect 3 0 trials
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6 sub-types
- Atrioventricular septal defect 0 trials
- Atrioventricular septal defect 4 0 trials
- Atrioventricular septal defect 5 0 trials
- Complete atrioventricular canal 0 trials Sub-types →
- Congenital heart defects, multiple types, 4 0 trials
- Partial atrioventricular canal 0 trials
Most studied deeper sub-types
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App-Based exercise program aims to strengthen hearts in congenital disease
Disease control Stopped earlyThis study tests a remote, app-enabled exercise program designed for people aged 10 to 50 with congenital heart disease. Participants use a smartphone app with exercise modules and wearable devices to track heart rate and progress. The goal is to see if this approach can safely i…
Sponsor: Duke University • Aim: Disease control
Last updated Aug 07, 2026 00:00 UTC
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Heart hole closure for migraines? tiny study halted early
Symptom relief Stopped earlyThis study tested whether closing a small hole in the heart (called a PFO) with a device could reduce migraine headaches. It planned to compare the real procedure to a sham (fake) procedure in adults aged 18-55 with frequent migraines. However, the study was stopped early after e…
Sponsor: W.L.Gore & Associates • Aim: Symptom relief
Last updated Jun 27, 2026 13:04 UTC