Hairy cell leukemia
MONDO:0018935Hairy cell leukemia (HCL) is a rare type of leukemia in which abnormal B-lymphocytes are present in the bone marrow, spleen and peripheral blood. It is a slowly progressive chronic lymphocytic leukemia (CLL). The name comes from the abnormally shaped lymphocytes with hair-like projections.
Also known as: HCL, HCL-C, hairy cell leukemia, leukemic reticuloendotheliosis, classic hairy cell leukaemia, classic hairy cell leukemia
2056 clinical trials for this condition and its sub-types, 40 tagged with Hairy cell leukemia itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Hairy cell leukemia
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Hairy cell leukemia variant 9 trials
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Refractory hairy cell leukemia 9 trials
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Experimental CAR T-Cell therapy targets rare B-Cell cancers
Disease control Stopped earlyThis phase 2 study tested a treatment called brexucabtagene autoleucel, a CAR T-cell therapy made from a patient's own immune cells, for four rare B-cell cancers: Waldenstrom macroglobulinemia, Richter transformation, Burkitt lymphoma, and hairy cell leukemia. The trial enrolled …
Phase 2 • Sponsor: Kite, A Gilead Company • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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Leukemia drug pill tested against IV version – but study halted early
Knowledge-focused Stopped earlyThis very early study aimed to compare an oral (pill) version of the chemotherapy drug cladribine with the standard IV (vein) version in people with certain leukemias. Only 3 people took part before the study was stopped early. The main goal was to see how the body handles the or…
Phase 1 • Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Aug 01, 2026 00:00 UTC