Hailey-Hailey disease
MONDO:0008218Benign chronic familial pemphigus of Hailey-Hailey is characterized by rhagades mostly located in the armpits, inguinal and perineal folds (scrotum, vulva).
Also known as: Hailey-Hailey disease, benign chronic familial pemphigus of Hailey-Hailey, benign chronic pemphigus, pemphigus, benign familial, BCPM, benign familial pemphigus, familial benign chronic pemphigus, familial benign pemphigus
41 clinical trials for this condition and its sub-types, 4 tagged with Hailey-Hailey disease itself.
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Last-Resort access to dupilumab for patients with severe inflammation
Disease control Expanded accessThis program provides compassionate use of dupilumab (Dupixent) for patients with severe type 2 inflammatory disorders who have no other treatment options. It aims to offer access to this drug outside of a clinical trial. The program is already approved for marketing.
Sponsor: Regeneron Pharmaceuticals • Aim: Disease control
Last updated Sep 03, 2026 00:00 UTC
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Gene therapy gel targets rare blistering skin disease
Disease control Recruiting nowThis early study tests a new gene therapy gel called KB111 for Hailey-Hailey disease, a rare genetic condition that causes painful blisters and skin lesions. The gel uses a modified virus to deliver a working copy of the faulty gene directly to the skin. The trial enrolls about 7…
Early phase 1 • Sponsor: Krystal Biotech, Inc. • Aim: Disease control
Last updated Jul 23, 2026 00:00 UTC
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New hope for rare, painful skin condition: drug trial underway
Disease control Recruiting nowThis study tests if guselkumab can help people with Hailey-Hailey disease, a genetic condition causing painful blisters and sores in skin folds. Ten adults with moderate to severe disease will receive the drug and be monitored for changes in skin severity and quality of life. The…
Phase 2 • Sponsor: Yale University • Aim: Disease control
Last updated Jun 27, 2026 14:01 UTC