Guillain-Barre syndrome

This study tests a single dose of tanruprubart (ANX005) in 30 adults and children with Guillain-Barré syndrome (GBS), a rare nerve disorder that causes weakness. The goal is to see how the drug works in the body, its early effects, and its safety. Participants must have GBS sympt…

This study compares two blood-filtering treatments—immunoadsorption and plasma exchange—for people with Guillain-Barré syndrome (GBS), a rare nerve disorder that can cause muscle weakness and paralysis. Researchers will enroll 20 adults to see which method is safer and more effec…

This study tests two breathing support devices—high-velocity nasal cannula (HVNI) and non-invasive ventilation (NIV)—in 80 adults with Guillain-Barré syndrome who have serious breathing trouble. The goal is to see which device helps more patients avoid needing a breathing tube wi…

This study compares a high-tech rehabilitation program—using robotic systems, virtual reality, and balance platforms—to standard physical therapy for people with acute neuromuscular diseases like Guillain-Barré syndrome. About 124 adults aged 18 to 80 will participate. The goal i…

This study aims to discover biological markers (biomarkers) that could help doctors diagnose and track neurological autoimmune diseases such as multiple sclerosis, myasthenia gravis, and Guillain-Barre syndrome. Researchers will analyze samples from 50,000 people, including patie…

This study follows 100 women with neuroimmune diseases (like multiple sclerosis or myasthenia gravis) through pregnancy and up to five years after. Researchers will track disease activity, pregnancy complications, and baby health to learn how these conditions affect fertility and…

This study reviews the medical records of 100 adults who were treated for Guillain-Barre Syndrome (GBS) at a single hospital in Switzerland. The goal is to better understand how often GBS occurs, what symptoms and nerve problems people have, what treatments they receive, and how …

This study looks at how children who had Guillain-Barré Syndrome (GBS) two to five years ago are doing emotionally and psychologically. Researchers will interview 25 children aged 10 or older to understand their memories, fears, and coping strategies. The goal is to learn what fa…

This study is looking for genetic clues that might explain why a very small number of people develop rare side effects like Guillain-Barré syndrome, blood clots with low platelets, or heart inflammation after a COVID-19 vaccine. Researchers will compare the DNA of people who had …

This study looks at whether ultrasound can detect nerve changes in people with Guillain-Barré syndrome (GBS) and chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) earlier than standard tests. Researchers will compare ultrasound images with nerve conduction studies …