Glucocorticoid-induced osteoporosis

MONDO:0000757

An osteoporosis caused by chronic glucocorticoid use. Glucocorticoids impair the replication, differentiation and function of osteoblasts and induce the apoptosis of mature osteoblasts and osteocytes; the also favor osteoclastogenesis leading to an increase in bone resorption.

Also known as: steroid-induced osteoporosis

6 clinical trials for this condition and its sub-types, 6 tagged with Glucocorticoid-induced osteoporosis itself.

Follow this condition to get notified about new trials

Where it sits in the disease tree

Browse by category →

Part of

↑ Corticosteroid-induced osteoporosis (6)

Including sub-types (6) Tagged with Glucocorticoid-induced osteoporosis (6)

Trials to join now! 2 Not yet recruiting 1 Not yet finished but already full! 1 Completed 2

Can a One-Year bone drug switch beat standard therapy for Steroid-Induced bone loss?

Disease control Not yet recruiting

This study follows people with bone loss caused by long-term steroid use to compare two treatment approaches. One group received romosozumab for the first year and then switched to denosumab, while the other group took denosumab throughout. After six years, researchers will measu…

Phase 4 • Sponsor: Tuen Mun Hospital • Aim: Disease control

Last updated Aug 14, 2026 00:00 UTC

Glucocorticoid-induced osteoporosis

Where it sits in the disease tree

Can a One-Year bone drug switch beat standard therapy for Steroid-Induced bone loss?