Glaucoma secondary to spherophakia/ectopia lentis and megalocornea
MONDO:0016559Glaucoma secondary to spherophakia/ectopia lentis and megalocornea is a rare, genetic, non-syndromic developmental defect of the eye disorder characterized by congenital megalocornea associated with spherophakia and/or ectopia lentis leading to pupillary block and secondary glaucoma. Additional features may include flat irides, iridodonesis, axial myopia, very deep anterior chambers, miotic, oval pupils without well-defined borders, ocular pain and irritability manifesting as conjunctival injection, corneal edema and central scarring, as well as a high arched palate.
Also known as: megalocornea-spherophakia-secondary glaucoma syndrome
8 clinical trials for this condition and its sub-types, 0 tagged with Glaucoma secondary to spherophakia/ectopia lentis and megalocornea itself.
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Can a simple office procedure ease glaucoma pressure?
Disease control Not yet recruitingThis study tests whether removing the ripcord from a glaucoma drainage device more than 3 months after placement lowers eye pressure. Adults with glaucoma who have had the ripcord in place for over 3 months will have it removed during a routine clinic visit. Researchers will meas…
Sponsor: Duke University • Aim: Disease control
Last updated Sep 05, 2026 00:00 UTC
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Which eye implant best tames glaucoma? a head-to-head trial aims to find out.
Disease control Not yet recruitingThis trial compares two surgical implants—the Baerveldt Glaucoma Implant and the Paul Glaucoma Implant—in people with glaucoma that is not well controlled by eye drops. Both devices are tiny tubes placed in the eye to drain fluid and lower pressure. The study will track which imp…
Phase 4 • Sponsor: University of Sydney • Aim: Disease control
Last updated Aug 05, 2026 00:00 UTC