Generalized pustular psoriasis
MONDO:0100491A rare and extreme form of psoriasis characterized by the appearance of sterile pustules which can take many patterns. All the main pathological features of the disease are accentuated. Generalized pustular psoriasis is clinically heterogeneous in its age at onset, precipitants, severity, and natural history. Many overlapping clinical entities are recognized. There is a relationship between these entities and plaque psoriasis, as some individuals may have episodes of plaque psoriasis preceding or following the generalized pustular psoriasis, but in others generalized pustular psoriasis occurs as the sole phenotype without plaque psoriasis at any time.
17 clinical trials for this condition and its sub-types, 16 tagged with Generalized pustular psoriasis itself.
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Sub-types of Generalized pustular psoriasis
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Psoriasis 14, pustular 0 trials
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Can immune fingerprints unlock new treatments for skin disease?
Knowledge-focused Not yet recruitingThis observational study aims to map the immune and molecular profiles of people with inflammatory skin conditions, including genetic forms like epidermolysis bullosa. By comparing these profiles to those of healthy individuals, researchers hope to identify unique signatures that…
Sponsor: Guy's and St Thomas' NHS Foundation Trust • Aim: Knowledge-focused
Last updated Aug 20, 2026 00:00 UTC
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Costa rica launches national registry to track rare skin disease
Knowledge-focused Not yet recruitingThis study creates a national registry for people with generalized pustular psoriasis (GPP) in Costa Rica. Researchers will collect information from about 50 patients to better understand the disease, how it progresses, and what treatments are used. The goal is to improve care fo…
Sponsor: Caja Costarricense de Seguro Social • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC