Gallstones

This study in Zimbabwe will screen women of childbearing age and high school students for HPV and Hepatitis B, then offer vaccines to those who are eligible. It also includes cognitive behavioral therapy for mental health issues. The goal is to see if this combined approach can p…

This trial is testing whether an experimental drug called anrikefon can improve recovery and reduce pain after laparoscopic gallbladder removal, compared to a standard painkiller. Adults undergoing this surgery will receive either anrikefon or the standard drug, and their pain le…

This study compares two drugs, ketamine and fentanyl, added to a standard numbing medicine (bupivacaine) to control pain after laparoscopic gallbladder removal. 84 adults aged 20-50 will receive one of the two combinations during surgery. The goal is to see which provides longer-…

This study investigates whether two specific gene variants (ABCG8 and UGT1A1) are linked to gallstone disease that requires gallbladder removal after bariatric surgery. Researchers compare adults who had weight-loss surgery and later needed their gallbladder removed with those wh…

This study looks at whether telling people with gallstones about the environmental impact of surgery affects their choice between having surgery or taking a 'wait and see' approach. About 400 patients from Dutch hospitals will use a special decision aid that includes eco-informat…