Fuchs' endothelial dystrophy
MONDO:0005321Fuchs endothelial corneal dystrophy (FECD) is the most frequent form of posterior corneal dystrophy and is characterized by excrescences on a thickened Descemet membrane (corneal guttae), generalized corneal edema, with gradually decreased visual acuity.
Also known as: Endoepithelial corneal dystrophy, FECD, Fuchs endothelial dystrophy, corneal dystrophy, Fuchs endothelial, late hereditary endothelial dystrophy, Fuchs endothelial corneal dystrophy
40 clinical trials for this condition and its sub-types, 33 tagged with Fuchs' endothelial dystrophy itself.
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Sub-types of Fuchs' endothelial dystrophy
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One shot to see clearly: cell therapy takes on corneal edema
Cure Not yet recruitingThis phase 2 trial tests whether a single injection of EO2002, made from magnetic human corneal endothelial cells, can safely improve vision in people with corneal edema caused by endothelial dysfunction. Participants receive either a low or high dose of cells or a placebo inject…
Phase 2 • Sponsor: Emmecell • Aim: Cure
Last updated Jul 31, 2026 00:00 UTC
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New eye test spots brain fog after cornea surgery
Diagnosis Not yet recruitingThis study checks if a special thinking test (MoCA Blind) can find memory or thinking problems after cornea surgery. It includes 200 adults with cornea disease who will take the test before and 90 days after surgery. The goal is to give doctors a better way to spot these issues i…
Sponsor: The S.N. Fyodorov Eye Microsurgery State Institution • Aim: Diagnosis
Last updated Jun 27, 2026 09:07 UTC
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New lens aims to sharpen sight after dual eye surgery
Symptom relief Not yet recruitingThis study will test a new type of artificial lens, called the PureSee IOL, in 10 people who need surgery for both cataracts and a cornea condition called Fuchs dystrophy. The goal is to see if this lens helps patients see well at different distances and reduces their need for gl…
Sponsor: Universitair Ziekenhuis Brussel • Aim: Symptom relief
Last updated Aug 27, 2026 00:00 UTC
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Fuchs dystrophy and cataract surgery: does the cornea behave differently?
Knowledge-focused Not yet recruitingThis observational study compares corneal thickness six weeks after routine cataract surgery in people with Fuchs endothelial corneal dystrophy (FECD) versus those without the condition. Researchers aim to see whether FECD eyes swell more or recover differently after surgery. Par…
Sponsor: Vienna Hospital Association • Aim: Knowledge-focused
Last updated Aug 12, 2026 00:00 UTC