Familial isolated arrhythmogenic right ventricular dysplasia

MONDO:0016342

Familial isolated arrhythmogenic right ventricular dysplasia (ARVC) is the familial autosomal dominant form of ARVC, a heart muscle disease characterized by life-threatening ventricular arrhythmias with left bundle branch block configuration that may manifest with palpitations, ventricular tachycardia, syncope and sudden fatal attacks, and that is due to dystrophy and fibro-fatty replacement of the right ventricular myocardium that may lead to right ventricular aneurysms.

Also known as: familial isolated ARVC, familial isolated ARVD, familial isolated arrhythmogenic right ventricular cardiomyopathy, familial isolated arrhythmogenic right ventricular dysplasia, familial isolated arrhythmogenic ventricular cardiomyopathy, familial isolated arrhythmogenic ventricular dysplasia

19 clinical trials for this condition and its sub-types, 0 tagged with Familial isolated arrhythmogenic right ventricular dysplasia itself.

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Where it sits in the disease tree

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↑ Familial cardiomyopathy (219) ↑ Arrhythmogenic right ventricular cardiomyopathy (32)

Sub-types of Familial isolated arrhythmogenic right ventricular dysplasia

Arrhythmogenic right ventricular dysplasia 9 5 trials
Arrhythmogenic right ventricular dysplasia 1 3 trials
Familial isolated arrhythmogenic ventricular dysplasia, left dominant form 3 trials
Catecholaminergic polymorphic ventricular tachycardia 1 2 trials
Arrhythmogenic right ventricular dysplasia 10 0 trials
Arrhythmogenic right ventricular dysplasia 11 0 trials
Arrhythmogenic right ventricular dysplasia 12 0 trials
Arrhythmogenic right ventricular dysplasia 13 0 trials
Arrhythmogenic right ventricular dysplasia 3 0 trials
Arrhythmogenic right ventricular dysplasia 4 0 trials
Arrhythmogenic right ventricular dysplasia 5 0 trials
Arrhythmogenic right ventricular dysplasia 6 0 trials
Arrhythmogenic right ventricular dysplasia 8 0 trials
Arrhythmogenic right ventricular dysplasia, familial, 14 0 trials
Familial isolated arrhythmogenic ventricular dysplasia, biventricular form 0 trials
Familial isolated arrhythmogenic ventricular dysplasia, right dominant form 0 trials

Including sub-types (19) Tagged with Familial isolated arrhythmogenic right ventricular dysplasia (0)

Trials to join now! 9 Not yet recruiting 1 Not yet finished but already full! 6 Completed 2 Terminated 1

Heart drug study halted early: what we know

Disease control Stopped early

This study tested an experimental drug called CRD-4730 in people with a rare inherited heart rhythm disorder (CPVT) that can cause dangerous fast heartbeats. Seven adults received two different doses of the drug and a placebo to check safety and how the body processes it. The stu…

Phase 2 • Sponsor: Cardurion Pharmaceuticals, Inc. • Aim: Disease control

Last updated Jun 27, 2026 12:38 UTC

Familial isolated arrhythmogenic right ventricular dysplasia

Where it sits in the disease tree

Heart drug study halted early: what we know