Extramedullary plasmacytoma
MONDO:0002754A plasma cell neoplasm arising at an extraosseous site. There is no involvement of the bone marrow. It most frequently involves the oropharynx, nasopharynx, sinuses, and larynx. Other sites of involvement include the gastrointestinal tract, central nervous system, breast, skin, lymph nodes, and bladder. A minority of patients have a monoclonal gammopathy. Treatment includes radiation therapy. Progression to plasma cell myeloma occurs in a minority of patients.
Also known as: extramedullary plasmacytoma, extramedullary plasmacytoma (clinical), extraosseous plasmacytoma, plasmacytoma, extramedullary, plasmacytoma, extramedullary (not occurring in bone), EP
1935 clinical trials for this condition and its sub-types, 7 tagged with Extramedullary plasmacytoma itself.
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Can a PET-MRI tracer reveal where CAR-T cells go in myeloma?
Disease control OngoingThis phase 1 trial tests whether a special imaging tracer can track CAR-T cells in people with extramedullary myeloma, a type of myeloma that forms tumors outside the bone marrow. Participants receive cilta-cel, a CAR-T therapy targeting the BCMA protein on myeloma cells, along w…
Phase 1 • Sponsor: Peter MacCallum Cancer Centre, Australia • Aim: Disease control
Last updated Jul 30, 2026 00:00 UTC
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New drug cocktail targets Hard-to-Treat myeloma spread
Disease control OngoingThis study tests a combination of four drugs (daratumumab, bortezomib, cyclophosphamide, and dexamethasone) in 41 people with multiple myeloma that has spread outside the bones, known as extramedullary disease. The goal is to see how well the treatment works and how safe it is. P…
Phase 2 • Sponsor: Stichting European Myeloma Network • Aim: Disease control
Last updated Jun 27, 2026 12:10 UTC
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New strategy aims to tame common virus after stem cell transplants
Disease control OngoingThis study tests a modified plan to prevent and treat cytomegalovirus (CMV) infection in people with blood cancers who have had a donor stem cell transplant. CMV is a common virus that can cause serious problems after transplant. The study involves 153 participants and looks at w…
Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC