Exstrophy-epispadias complex

MONDO:0017919

A spectrum of genitourinary malformations ranging in severity from epispadias (E) and classical bladder exstrophy (CEB) to exstrophy of the cloaca (EC) as the most severe form. Depending on severity, the EEC may involve the urinary system, the musculoskeletal system, the pelvis, the pelvic floor, the abdominal wall, the genitalia and sometimes the spine and the anus.

Also known as: EEC, OEIS complex, OEIS syndrome, BEEC, bladder exstrophy-epispadias-cloacal extrophy complex

3 clinical trials for this condition and its sub-types, 1 tagged with Exstrophy-epispadias complex itself.

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Where it sits in the disease tree

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Part of

↑ Kidney disorder (4032) ↑ Urogenital tract malformation (8)

Sub-types of Exstrophy-epispadias complex

Bladder exstrophy 3 trials
Bladder exstrophy-epispadias-cloacal extrophy complex 1 trial
Cloacal exstrophy 0 trials
Epispadias 0 trials

Including sub-types (3) Tagged with Exstrophy-epispadias complex (1)

Completed 1

Blood-Based bandage may cut surgery complications in rare bladder condition

Disease control Completed

This study tested whether a special material made from a child's own blood, called platelet-rich fibrin (PRF), can reduce complications after surgery for a rare bladder condition called bladder exstrophy. Twenty children having their first bladder repair surgery were split into t…

Sponsor: National Children's Medical Center, Uzbekistan • Aim: Disease control

Last updated Jun 27, 2026 08:07 UTC

Exstrophy-epispadias complex

Where it sits in the disease tree

Blood-Based bandage may cut surgery complications in rare bladder condition